Evidence map›Paper›PMID 31296579›Full record

ArticleHaematologica2020

Pre-transplant testosterone and outcome of men after allogeneic stem cell transplantation.

Aleksandar Radujkovic, Lambros Kordelas, Julia Krzykalla, Axel Benner, David Schult, Joshua Majer-Lauterbach, Dietrich W Beelen, Carsten Müller-Tidow, Christian Kasperk, Peter Dreger and 1 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Aleksandar RadujkovicDepartment of Internal Medicine V, University of Heidelberg, Heidelberg.
Lambros KordelasDepartment of Bone Marrow Transplantation, University Hospital, Essen.
Julia KrzykallaDivision of Biostatistics, German Cancer Research Center, Heidelberg.
Axel BennerDivision of Biostatistics, German Cancer Research Center, Heidelberg.
David SchultDepartment of Internal Medicine V, University of Heidelberg, Heidelberg.
Joshua Majer-LauterbachDepartment of Internal Medicine V, University of Heidelberg, Heidelberg.
Dietrich W BeelenDepartment of Bone Marrow Transplantation, University Hospital, Essen.
Carsten Müller-TidowDepartment of Internal Medicine V, University of Heidelberg, Heidelberg.
Christian KasperkDepartment of Internal Medicine I, University of Heidelberg, Heidelberg, Germany.
Peter DregerDepartment of Internal Medicine V, University of Heidelberg, Heidelberg.
Thomas LuftDepartment of Internal Medicine V, University of Heidelberg, Heidelberg thomas.luft@med.uni-heidelberg.de.
Heidelberg University · DEEssen University Hospital · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Testosterone is an important determinant of endothelial function and vascular health in men. As both factors play a role in mortality after allogeneic stem cell transplantation (alloSCT), we retrospectively evaluated the impact of pre-transplant testosterone levels on outcome in male patients undergoing alloSCT. In the discovery cohort (n=346), an impact on outcome was observed only in the subgroup of patients allografted for acute myeloid leukemia (AML) (n=176, hereafter termed 'training cohort'). In the training cohort, lower pre-transplant testosterone levels were significantly associated with shorter overall survival (OS) [hazard ratio (HR) for a decrease of 100 ng/dL: 1.11,

Indexed as

Hematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteHumansMaleProspective StudiesRetrospective StudiesStem Cell TransplantationTestosteroneTransplantation ConditioningTransplantation, HomologousTestosterone

Identifiers

PMID31296579
PMCPMC7193480
OpenAlexW2962170726

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.