Evidence map›Paper›PMID 31296576›Full record

ArticleHaematologica2020

Blood transcriptome and clonal T-cell correlates of response and non-response to eltrombopag therapy in a cohort of patients with chronic immune thrombocytopenia.

Haiyu Zhang, Bing M Zhang, Xiangqian Guo, Liwen Xu, Xiaoqing You, Robert B West, James B Bussel, James L Zehnder

Abstract readLetter
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Safety and efficacy of eltrombopag in the treatment of children with immune thrombocytopenia: a Meta analysis.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Pathogenesis of refractory ITP: Overview.British journal of haematology · 2023
    Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haiyu ZhangDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.
Bing M ZhangDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.
Xiangqian GuoDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.
Liwen XuDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.
Xiaoqing YouDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.
Robert B WestDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.
James B BusselPlatelet Disorders Center, Department of Pediatrics, Weill-Cornell Medicine, New York, NY, USA.
James L ZehnderDepartment of Pathology, School of Medicine, Stanford University, Stanford, CA, USA zehnder@stanford.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Purpura, Thrombocytopenic, IdiopathicBenzoatesHumansHydrazinesPyrazolesT-LymphocytesTranscriptomeBenzoateseltrombopagHydrazinesPyrazoles

Identifiers

PMID31296576
PMCPMC7049341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.