Evidence map›Paper›PMID 31296523›Full record

Observational studyAJNR. American journal of neuroradiology2019

One-Stop Management with Perfusion for Transfer Patients with Stroke due to a Large-Vessel Occlusion: Feasibility and Effects on In-Hospital Times.

A Brehm, I Tsogkas, I L Maier, H J Eisenberg, P Yang, J-M Liu, J Liman, M-N Psychogios

Registry-linked trialOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05644938 (Optimizing Door-to-reperfusion Times of One-stop Management in Acute Ischemic Stroke Trial), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05644938 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Optimizing Door-to-reperfusion Times of One-stop Management in Acute Ischemic Stroke Trial

TypeinterventionalSponsorCan Tho Stroke International Services HospitalRan2023 to 2023Enrolled50ConditionsAcute Ischemic StrokeArmsStandard workflow, One-stop
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Optimizing Door-to-Groin Puncture Time: The Mayo Clinic Experience.Mayo Clinic proceedings. Innovations, quality & outcomes · 2022
    Article
  11. Article
  12. Article
  13. Observational
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

A BrehmFrom the Departments of Neuroradiology (A.B., I.T., H.J.E., M.-N.P.) Alex.brehm@med.uni-goettingen.de.ORCID 0000-0002-1630-6210
I TsogkasFrom the Departments of Neuroradiology (A.B., I.T., H.J.E., M.-N.P.).ORCID 0000-0003-2561-9603
I L MaierNeurology (I.L.M., H.J.E., J.L.), University Medical Center Goettingen, Goettingen, Germany.ORCID 0000-0001-6988-8878
H J EisenbergFrom the Departments of Neuroradiology (A.B., I.T., H.J.E., M.-N.P.).ORCID 0000-0001-6614-4275
P YangDepartment of Neurosurgery (P.Y., J.-M.L.), Changhai Hospital, Second Military Medical University, Changhai, China.ORCID 0000-0002-6154-3602
J-M LiuDepartment of Neurosurgery (P.Y., J.-M.L.), Changhai Hospital, Second Military Medical University, Changhai, China.ORCID 0000-0003-2768-7298
J LimanNeurology (I.L.M., H.J.E., J.L.), University Medical Center Goettingen, Goettingen, Germany.ORCID 0000-0002-7465-9655
M-N PsychogiosFrom the Departments of Neuroradiology (A.B., I.T., H.J.E., M.-N.P.).ORCID 0000-0002-0016-414X
University Hospital of Basel · CHUniversity of Göttingen · DESecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeIn-hospital time delays lead to a relevant deterioration of neurologic outcomes in patients with stroke with large-vessel occlusions. At the moment, CT perfusion is relevant in the triage of late-window patients with stroke. We conducted this study to determine whether one-stop management with perfusion is feasible and leads to a reduction of in-hospital times. MATERIALS AND

methodsIn this observational study, we report the first 15 consecutive transfer patients with stroke with externally confirmed large-vessel occlusions who underwent flat panel detector CT perfusion and thrombectomy in the same room. Preinterventional imaging consisted of noncontrast flat panel detector CT and flat panel detector CT perfusion, acquired with a biplane angiography system. The flat panel detector CT perfusion was used to reconstruct a flat panel detector CT angiography to confirm the large-vessel occlusions. After confirmation of the large-vessel occlusion, the patient underwent mechanical thrombectomy. We recorded time metrics and safety parameters prospectively and compared them with those of transfer patients whom we treated before the introduction of one-stop management with perfusion.

resultsFifteen transfer patients underwent flat panel detector CT perfusion and were treated with mechanical thrombectomy from June 2017 to January 2019. The median time from symptom onset to admission was 241 minutes. Median door-to-groin time was 24 minutes. Compared with 23 transfer patients imaged with multidetector CT, it was reduced significantly (24 minutes; 95% CI, 19-37 minutes, versus 53 minutes; 95% CI, 44-66 minutes;

conclusionsIn this small series, one-stop management with perfusion led to a significant reduction of in-hospital times compared with our previous workflow.

Indexed as

Patient TransferTime-to-TreatmentAgedAged, 80 and overComputed Tomography AngiographyFeasibility StudiesFemaleHumansMaleMiddle AgedPerfusion ImagingRetrospective StudiesStrokeThrombectomyWorkflow

Identifiers

PMID31296523
PMCPMC7048466
OpenAlexW2961048286

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.