ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2019
Longitudinal changes of microbiome composition and microbial metabolomics after surgical weight loss in individuals with obesity.
Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 5 of them syntheses that pooled it.
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Who cites it
56 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Roles of the gut microbiome in weight management.Nature reviews. Microbiology · 2023Pooled it
- Pooled it
- THE INTESTINAL MICROBIOME IN PATIENTS UNDERGOING BARIATRIC SURGERY: A SYSTEMATIC REVIEW.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022 · on this mapPooled it
- Gut Microbiota, Probiotics and Psychological States and Behaviors after Bariatric Surgery-A Systematic Review of Their Interrelation.Nutrients · 2020Pooled it
- Pooled it
- Reshaping of the fecal proteome and metaproteome in obese patients 2 years after bariatric surgery.mSystems · 2026Trial
- Metabolites and diabetes remission after weight loss.Nutrition & diabetes · 2021Trial
- Effects of Diet versus Gastric Bypass on Metabolic Function in Diabetes.The New England journal of medicine · 2020Trial
- Escherichia coli as a gut microbial marker of obesity and its reduction following bariatric treatment.Journal of gastroenterology · 2026Article
- Gut Microbiota-Derived Extracellular Vesicles in Patients With Obesity Undergoing Gastric Bypass Surgery.Molecular microbiology · 2026Article
- The Role of Gut Microbiome in Obesity and Weight Management: A Review of Current Evidence and Future Directions.Food science & nutrition · 2026Review
- Daily fiber supplementation after bariatric surgery demonstrates tolerability and influence on the fecal gut microbiome.Frontiers in nutrition · 2026Article
- Reshaping the Gut: Symptoms, Nutrition and Microbiota After Bariatric and Endoscopic Procedures in Obesity.Nutrients · 2025Review
- Multi-omics analysis of bariatric surgery's impact on type 2 diabetes and prediabetes.Scientific reports · 2025Article
- Site-Specific Gut Microbiome Changes After Roux-en-Y Gastric Bypass in Rats: Effects of a Multicomponent Bovine Colostrum-Based Complex.International journal of molecular sciences · 2025Article
- Beyond weight loss: exploring the neurological ramifications of altered gut microbiota post-bariatric surgery.Journal of translational medicine · 2025Review
- Altered gut microbiome and serum metabolome profiles associated with essential tremor.Metabolic brain disease · 2025Article
- A Pilot Study of the Gut Microbiota in Spine Fusion Surgery Patients.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2025Article
- Changes in energy homeostasis, gut peptides, and gut microbiota in Emiratis with obesity after bariatric surgery.PloS one · 2025Article
- Multi-omics insights into the microbiota-gut-brain axis and cognitive improvement post-bariatric surgery.Journal of translational medicine · 2024Article
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Authors and funding
9 authors.
Funding
Abstract
backgroundSome of the metabolic effects of bariatric surgery may be mediated by the gut microbiome.
objectivesTo study the effect of bariatric surgery on changes to gut microbiota composition and bacterial pathways, and their relation to metabolic parameters after bariatric surgery. SETTINGS: University hospitals in the United States and Spain.
methodsMicrobial diversity and composition by 16 S rRNA sequencing, putative bacterial pathways, and targeted circulating metabolites were studied in 26 individuals with severe obesity, with and without type 2 diabetes, before and at 3, 6, and 12 months after either gastric bypass or sleeve gastrectomy.
resultsBariatric surgery tended to increase alpha diversity, and significantly altered beta diversity, microbiota composition, and function up to 6 months after surgery, but these changes tend to regress to presurgery levels by 12 months. Twelve of 15 bacterial pathways enriched after surgery also regressed to presurgery levels at 12 months. Network analysis identified groups of bacteria significantly correlated with levels of circulating metabolites over time. There were no differences between study sites, surgery type, or diabetes status in terms of microbial diversity and composition at baseline and after surgery.
conclusionsThe association among changes in microbiome with decreased circulating biomarkers of inflammation, increased bile acids, and products of choline metabolism and other bacterial pathways suggest that the microbiome partially mediates improvement of metabolism during the first year after bariatric surgery.
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