Evidence map›Paper›PMID 31296131›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

Hyperemia in subarachnoid hemorrhage patients is associated with an increased risk of seizures.

Ayham Alkhachroum, Murad Megjhani, Kalijah Terilli, Clio Rubinos, Jenna Ford, Brendan K Wallace, David J Roh, Sachin Agarwal, E Sander Connolly, Amelia K Boehme and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Spontaneous subarachnoid haemorrhage.Lancet (London, England) · 2022
    Review
  10. Role of hydrogen sulfide in subarachnoid hemorrhage.CNS neuroscience & therapeutics · 2022
    Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Ayham AlkhachroumDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Murad MegjhaniDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Kalijah TerilliDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.ORCID 0000-0003-2198-5147
Clio RubinosDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Jenna FordDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Brendan K WallaceDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
David J RohDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Sachin AgarwalDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
E Sander ConnollyDepartment of Neurosurgery, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Amelia K BoehmeDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Jan ClaassenDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Soojin ParkDepartment of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Columbia University · US

Funding

Miami Clinical and Translational Science InstituteUL1TR002736 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, KOBETZ, ERIN N · 2018 to 2022
$23.2M
Multiparametric Prediction of Vasospasm after Subarachnoid HemorrhageK01ES026833 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PARK, SOOJIN · 2015 to 2019
$1.1M
NCATS NIH HHS UL1 TR002736NIEHS NIH HHS K01 ES026833
6 · The paper itself

Abstract

The association between impaired brain perfusion, cerebrovascular reactivity status and the risk of ictal events in patients with subarachnoid hemorrhage is unknown. We identified 13 subarachnoid hemorrhage (SAH) patients with seizures and 22 with ictal-interictal continuum (IIC), and compared multimodality physiological recordings to 38 similarly poor-grade SAH patients without ictal activity. We analyzed 10,179 cumulative minutes of seizure and 12,762 cumulative minutes of IIC. Cerebrovascular reactivity (PRx) was not different between subjects with seizures, IIC, or controls. Cerebral perfusion pressure (CPP) was higher in patients with seizures [99 ± 6.5,

Indexed as

AgedBrainCerebrovascular CirculationFemaleHomeostasisHumansHyperemiaMaleMiddle AgedRisk FactorsSeizuresSubarachnoid Hemorrhagecerebral perfusionelectroencephalogramictal-interictal continuumSeizuressubarachnoid hemorrhage

Identifiers

PMID31296131
PMCPMC7238374
OpenAlexW2956808619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.