Evidence map›Paper›PMID 31296130›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020

microRNA-367-3p regulation of GPRC5A is suppressed in ischemic stroke.

Fatiha Tabet, Seyoung Lee, Wanying Zhu, Michael G Levin, Cynthia L Toth, Luisa F Cuesta Torres, Antony Vinh, Hyun Ah Kim, Hannah X Chu, Megan A Evans and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. MicroRNA Profiles in Critically Ill Patients.Current medicinal chemistry · 2024
    Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Fatiha TabetMechanisms of Disease and Translational Research, School of Medical Sciences, University of New South Wales, Sydney, Australia.
Seyoung LeeDepartment of Pharmacology, Monash University, Melbourne, Victoria, Australia.
Wanying ZhuDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Michael G LevinNational Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Cynthia L TothDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Luisa F Cuesta TorresMechanisms of Disease and Translational Research, School of Medical Sciences, University of New South Wales, Sydney, Australia.
Antony VinhDepartment of Pharmacology, Monash University, Melbourne, Victoria, Australia.
Hyun Ah KimDepartment of Pharmacology, Monash University, Melbourne, Victoria, Australia.
Hannah X ChuDepartment of Pharmacology, Monash University, Melbourne, Victoria, Australia.
Megan A EvansDepartment of Pharmacology, Monash University, Melbourne, Victoria, Australia.
Meaghan E KuzmichDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Grant R DrummondDepartment of Pharmacology, Monash University, Melbourne, Victoria, Australia.
Alan T RemaleyNational Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Kerry-Anne RyeMechanisms of Disease and Translational Research, School of Medical Sciences, University of New South Wales, Sydney, Australia.
Christopher G SobeyDepartment of Pharmacology, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0001-6525-9097
Kasey C VickersDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-5643-3102
La Trobe University · AUVanderbilt University Medical Center · USUNSW Sydney · AUMonash University · AUNational Institutes of Health · US

Funding

Non-coding RNA & Bioinformatics CoreP01HL116263 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VICKERS, KASEY C · 2014 to 2025
$24.7M
HDL-microRNA Intercellular Communication in AtherosclerosisR01HL128996 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI VICKERS, KASEY C · 2015 to 2019
$2.3M
Macrophage SR-BI Regulates Autophagy, Angiogenin and tRNA-derived small RNAsR01HL127173 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI LINTON, MACRAE F, VICKERS, KASEY C · 2016 to 2019
$2.1M
Circulating microRNAs Control Cholesterol Homeostasis through hepatic mechanismsK22HL113039 · NHLBI · VANDERBILT UNIVERSITY · PI VICKERS, KASEY C · 2013 to 2015
$746k
NHLBI NIH HHS K22 HL113039NHLBI NIH HHS P01 HL116263NHLBI NIH HHS R01 HL127173NHLBI NIH HHS R01 HL128996
6 · The paper itself

Abstract

Ischemic stroke is a major cause of mortality and long-term disability with limited treatment options, and a greater understanding of the gene regulatory mechanisms underlying ischemic stroke-associated neuroinflammation is required for new therapies. To study ischemic stroke

Indexed as

AnimalsGene Expression RegulationInflammationIschemic StrokeMaleMiceMice, Inbred C57BLMicroRNAsReceptors, G-Protein-CoupledGPRC5A protein, mouseMicroRNAsMIRN367 microRNA, mouseReceptors, G-Protein-CoupledbrainischemiaMicrornaneuroinflammationneuronsstroke

Identifiers

PMID31296130
PMCPMC7238381
OpenAlexW2958864469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.