Evidence map›Paper›PMID 31295741›Full record

ReviewGerontology2019

New Trend in Old-Age Mortality: Gompertzialization of Mortality Trajectory.

Leonid A Gavrilov, Natalia S Gavrilova

Open access · bronzeAbstract readReview
In one paragraph

Review in Gerontology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Biological Restraints on Indefinite Survival.Cold Spring Harbor perspectives in medicine · 2023
    Review
  12. Review
  13. Centenarians may hold a key to continued rise of human longevity.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Are We Approaching a Biological Limit to Human Longevity?The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Article
  18. Article
  19. THE EXPOSOME IN HUMAN EVOLUTION: FROM DUST TO DIESEL.The Quarterly review of biology · 2019
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Leonid A GavrilovAcademic Research Centers, NORC at the University of Chicago, Chicago, Illinois, USA, gavrilov@longevity-science.org.
Natalia S GavrilovaAcademic Research Centers, NORC at the University of Chicago, Chicago, Illinois, USA.
University of Chicago · US

Funding

Biodemography of Old-Age MortalityR21AG054849 · NIA · NATIONAL OPINION RESEARCH CENTER · PI GAVRILOVA, NATALIA S · 2017 to 2018
$428k
NIA NIH HHS R21 AG054849
6 · The paper itself

Abstract

There is great interest among gerontologists, demographers, and actuaries in the question concerning the limits to human longevity. Attempts at getting answers to this important question have stimulated many studies on late-life mortality trajectories, often with opposing conclusions. One group of researchers believes that mortality stops growing with age at extreme old ages, and that hence there is no fixed limit to the human life span. Other studies found that mortality continues to grow with age up to extreme old ages. Our study suggests a possible solution to this controversy. We found that mortality deceleration is best observed when older, less accurate life span data are analyzed, while in the case of more recent and reliable data there is a persistent mortality growth with age. We compared the performance (goodness of fit) of two competing mortality models - the Gompertz model and the Kannisto ("mortality deceleration") model - at ages of 80-105 years using data for 1880-1899 single-year birth cohorts of US men and women. The mortality modeling approach suggests a transition from mortality deceleration to the Gompertzian mortality pattern over time for both men and women. These results are consistent with the hypothesis about disappearing mortality deceleration over time due to improvement in the accuracy of age reporting. In the case of more recent data, mortality continues to grow with age even at very old ages. This observation may lead to more conservative estimates of future human longevity records.

Indexed as

LongevityAged, 80 and overFemaleHumansMaleModels, StatisticalMortalityUnited StatesAge misreportingBiodemographyGompertz lawKannisto modelLate-life mortalityLongevityMortality decelerationOld age

Identifiers

PMID31295741
PMCPMC6703938
OpenAlexW2945805818

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.