Evidence map›Paper›PMID 31295670›Full record

ArticleClinical biomechanics (Bristol, Avon)2019

Influence of relative injury risk profiles on anterior cruciate ligament and medial collateral ligament strain during simulated landing leading to a noncontact injury event.

Nathaniel A Bates, Nathan D Schilaty, Aaron J Krych, Timothy E Hewett

Abstract read
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nathaniel A BatesDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA; Department of Biomedical Engineering and Physiology, Mayo Clinic, Rochester, MN, USA; Sports Medicine Center, Mayo Clinic, Rochester, MN, USA. Electronic address: batesna@gmail.com.
Nathan D SchilatyDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA; Department of Biomedical Engineering and Physiology, Mayo Clinic, Rochester, MN, USA; Sports Medicine Center, Mayo Clinic, Rochester, MN, USA.
Aaron J KrychDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA; Department of Biomedical Engineering and Physiology, Mayo Clinic, Rochester, MN, USA.
Timothy E HewettDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA; Department of Biomedical Engineering and Physiology, Mayo Clinic, Rochester, MN, USA; Sports Medicine Center, Mayo Clinic, Rochester, MN, USA; Department of Physical Medicine & Rehabilitation, Mayo Clinic, Rochester, MN, USA.

Funding

Mayo Clinic Interdisciplinary Women's Health Research ProgramK12HD065987 · NICHD · MAYO CLINIC ROCHESTER · PI KANTARCI, KEJAL · 2010 to 2023
$6.7M
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female AthletesR01AR055563 · NIAMS · OHIO STATE UNIVERSITY · PI BATES, NATHANIEL ANDREW, KRYCH, AARON · 2008 to 2022
$5.9M
Multi-faceted Approach to Modeling ACL Injury MechanismsR01AR056259 · NIAMS · OHIO STATE UNIVERSITY · PI HEWETT, TIMOTHY E · 2009 to 2017
$4.9M
NIAMS NIH HHS L30 AR070273NIAMS NIH HHS R01 AR055563NIAMS NIH HHS R01 AR056259NICHD NIH HHS K12 HD065987
6 · The paper itself

Abstract

backgroundAthletes have traditionally been subdivided into risk classifications for ACL injury relative to the biomechanical traits they display during landing. This investigation aimed to discern whether these separate risk classifications elicit strain differences on the ACL and MCL during landing. It was hypothesized that the higher risk simulation profiles would exhibit greater ACL strain and that the ACL would exhibit greater strain than the MCL under all conditions.

methodThe mechanical impact simulator was used to simulate landing on a cohort of 46 cadaveric specimens. The simulator applied external joint loads to the knee prior to impulse delivery. These loads were organized into a series of profiles derived from in vivo motion capture previously performed on a cohort of 44 athletes and represented various risk classifications. Strain gauges were implanted on the ACL and MCL and simulations performed until a structural failure was elicited. Differences were assessed with Kruskal-Wallis tests.

findingsThe highest-risk profiles tended to exhibit greater peak ACL strain and change in ACL strain than the baseline- and moderate-risk profiles. Specimens that failed during lower-risk simulations expressed greater strain at these loads than specimens that completed higher-risk simulations. The ACL recorded greater strain than the MCL throughout all simulation profiles.

interpretationThis behavior justifies why neuromuscular interventions have greater impact on higher-risk athletes and supports the continued screening and targeted training of those athletes that express greater injury risk. The loading disparity between ACL and MCL justifies their limited concomitant injury rate.

Indexed as

AdultAnterior Cruciate LigamentAnterior Cruciate Ligament InjuriesAthletic InjuriesBiomechanical PhenomenaCadaverCollateral LigamentsFemaleHumansKnee InjuriesKnee JointMaleYoung Adult

Identifiers

PMID31295670
PMCPMC6823138

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.