Evidence map›Paper›PMID 31295522›Full record

ReviewAdvanced drug delivery reviews2019

Listening for the therapeutic window: Advances in drug delivery utilizing photoacoustic imaging.

Colman Moore, Fang Chen, Junxin Wang, Jesse V Jokerst

Abstract readReview
In one paragraph

Review in Advanced drug delivery reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Photoacoustic monitoring of angiogenesis predicts response to therapy in healing wounds.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society · 2022
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Colman MooreDepartment of NanoEngineering, University of California, San Diego, La Jolla, CA 92093, United States.
Fang ChenDepartment of NanoEngineering, University of California, San Diego, La Jolla, CA 92093, United States; Materials Science and Engineering Program, University of California, San Diego, La Jolla, CA 92093, United States.
Junxin WangDepartment of NanoEngineering, University of California, San Diego, La Jolla, CA 92093, United States.
Jesse V JokerstDepartment of NanoEngineering, University of California, San Diego, La Jolla, CA 92093, United States; Materials Science and Engineering Program, University of California, San Diego, La Jolla, CA 92093, United States; Department of Radiology, University of California, San Diego, La Jolla, CA 92093, United States. Electronic address: jjokerst@ucsd.edu.

Funding

Training in Multi-Scale Analysis of Biological Structure and FunctionT32EB009380 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Andrew D. McCulloch, Padmini Rangamani · 2009 to 2026
$4.8M
Therapeutic Drug Monitoring with a Wearable Ultrasound-based SensorDP2HL137187 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2016 to 2019
$2.7M
Modeling and analysis of the mechanochemical processes that govern clathrin-mediated endocytosisR01GM132106 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RANGAMANI, PADMINI · 2020 to 2024
$1.5M
Vevo LAZR Photoacoustic Imaging SystemS10OD021821 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HALL, DAVID J · 2016 to 2016
$594k
NHLBI NIH HHS DP2 HL137187NIBIB NIH HHS T32 EB009380NIGMS NIH HHS R01 GM132106NIH HHS S10 OD021821
6 · The paper itself

Abstract

The preclinical landscape of photoacoustic imaging has experienced tremendous growth in the past decade. This non-invasive imaging modality augments the spatiotemporal capabilities of ultrasound with optical contrast. While it has principally been investigated for diagnostic applications, many recent reports have described theranostic delivery systems and drug monitoring strategies using photoacoustics. Here, we provide an overview of the progress to date while highlighting work in three specific areas: theranostic nanoparticles, real-time drug monitoring, and stem cell ("living drug") tracking. Additionally, we discuss the challenges that remain to be addressed in this burgeoning field.

Indexed as

Diagnostic ImagingDrug Delivery SystemsPhotoacoustic TechniquesAnimalsContrast MediaDrug CarriersDrug MonitoringHumansNanostructuresNeoplasmsPhototherapyStem Cell TransplantationTheranostic NanomedicineContrast MediaDrug CarriersDrug deliveryNanoparticlesPhotoacousticsUltrasound

Identifiers

PMID31295522
PMCPMC6745251

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.