Evidence map›Paper›PMID 31295337›Full record

ArticlePloS one2019

Classifying hand sensorimotor functions of the chronic kidney disease patients using novel manual tactile test and pinch-holding-up activity.

I-Te Tu, Yu-Shiuan Cheng, Pu-Chun Mo, Hsiu-Yun Hsu, Li-Chieh Kuo, I-Ming Jou, Fong-Chin Su

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

I-Te TuDepartment of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.
Yu-Shiuan ChengDepartment of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.
Pu-Chun MoDepartment of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.
Hsiu-Yun HsuDepartment of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.
Li-Chieh KuoDepartment of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.
I-Ming JouDepartment of Orthopedics, E-Da Hospital, Kaohsiung, Taiwan.
Fong-Chin SuDepartment of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan.ORCID 0000-0002-3870-4842

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hand function deterioration brings about inconvenience to the daily lives of the chronic kidney disease patients. However, a full spectrum of hand function examination is absent. Therefore, this study aimed to classify the hand sensorimotor functions of the chronic kidney disease patients using the novel sensorimotor assessment tools, manual tactile test (MTT) and pinch-holding-up activity (PHUA) test, and explore the feasibility in comparison with traditional evaluations in the clinical practice. 68 stage-5 chronic kidney disease patients and 50 healthy subjects were recruited in this study. A series of conventional evaluations and two novel hand function tools, manual tactile test and pinch-holding-up activity test were conducted from the perspective of hand dexterity, sensory input threshold, force generation and sensorimotor control. Independent t-test was used to find out group differences and the receiver operating characteristic curve was used to determine accuracy of the tests. In our results, significant reduction of hand dexterity, sensory input, force generation and sensorimotor control was found in patients from an overall perspective. This trend was discovered to be the same when dividing the subjects into the old and young age group. From the receiver operator characteristic curves, nearly all the areas under the curve of all tests were over 0.8. The novel evaluation tools, the manual tactile test and pinch-holding-up activity, were found to have comparable or even better accuracy than the traditional ones. The shape and weight subtests of the manual tactile test displayed the highest accuracy. To sum up, by incorporating the novel and conventional assessment tests, this study built up the fundamental understanding of the hand functions in multiple dimensions and consolidate the clinical merits of applying the two novel tools, manual tactile test and pinch-holding-up activity, on chronic kidney disease patients.

Indexed as

AdultAgedAged, 80 and overFemaleHandHand StrengthHumansMaleMiddle AgedPinch StrengthRenal DialysisRenal Insufficiency, ChronicSensorimotor CortexSensory ThresholdsThumbTouch

Identifiers

PMID31295337
PMCPMC6623959

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.