Evidence map›Paper›PMID 31295102›Full record

ArticleIEEE transactions on bio-medical engineering2020

Robust Longitudinal Ankle Edema Assessment Using Wearable Bioimpedance Spectroscopy.

Samer Mabrouk, Sinan Hersek, Hyeon Ki Jeong, Daniel Whittingslow, Venu G Ganti, Paul Wolkoff, Omer T Inan

Abstract read
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Article in IEEE transactions on bio-medical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samer Mabrouk
Sinan Hersek
Hyeon Ki Jeong
Daniel Whittingslow
Venu G Ganti
Paul Wolkoff
Omer T Inan

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008169 · NIGMS · EMORY UNIVERSITY · PI GROSS, ROBERT E · 1987 to 2021
$20.3M
Wearable lung sounds, fluid, and body temperature monitoring for patients with COVID-19R01EB023808 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI INAN, OMER TOLGA · 2016 to 2020
$2.2M
NIBIB NIH HHS R01 EB023808NIGMS NIH HHS T32 GM008169
6 · The paper itself

Abstract

objectiveWe present a robust methodology for tracking ankle edema longitudinally based on bioimpedance spectroscopy (BIS).

methodsWe designed a miniaturized BIS measurement system and employed a novel calibration method that enables accurate, high-resolution measurements with substantially lower power consumption than conventional approaches. Using this state-of-the-art wearable BIS measurement system, we developed a differential measurement technique for robust assessment of ankle edema. This technique addresses many of the major challenges in longitudinal BIS-based edema assessment, including day-to-day variability in electrode placement, positional/postural variability, and intersubject variability.

resultsWe first evaluated the hardware in bench-top testing, and determined the error of the bioimpedance measurements to be 0.4 Ω for the real components and 0.54 Ω for the imaginary components with a resolution of 0.2 Ω. We then validated the hardware and differential measurement technique in: 1) an ex vivo, fresh-frozen, cadaveric limb model, and 2) a cohort of 11 human subjects for proof of concept (eight healthy controls and five subjects with recently acquired acute unilateral ankle injury).

conclusionThe hardware design, with novel calibration methodology, and differential measurement technique can potentially enable long-term quantification of ankle edema throughout the course of rehabilitation following acute ankle injuries. SIGNIFICANCE: This could lead to better-informed decision making regarding readiness to return to activities and/or tailoring of rehabilitation activities to an individual's changing needs.

Indexed as

AnkleWearable Electronic DevicesEdemaElectric ImpedanceHumansSpectrum Analysis

Identifiers

PMID31295102
PMCPMC7217444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.