Evidence map›Paper›PMID 31295065›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2019

Nutraceutical and pharmaceutical cocktails did not improve muscle function or reduce histological damage in D2-mdx mice.

Hannah R Spaulding, Tiffany Quindry, Kayleen Hammer, John C Quindry, Joshua T Selsby

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hannah R SpauldingDepartment of Animal Science, Iowa State University, Ames, Iowa.
Tiffany QuindryDepartment of Health and Human Performance, University of Montana, Missoula, Montana.
Kayleen HammerDepartment of Animal Science, Iowa State University, Ames, Iowa.
John C QuindryDepartment of Health and Human Performance, University of Montana, Missoula, Montana.
Joshua T SelsbyDepartment of Animal Science, Iowa State University, Ames, Iowa.
Iowa State University · USUniversity of Montana · US

Funding

Training and education CoreU54AR052646 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MCNALLY, ELIZABETH M, SWEENEY, H LEE · 2005 to 2020
$24.1M
NIAMS NIH HHS U54 AR052646
6 · The paper itself

Abstract

Progressive muscle injury and weakness are hallmarks of Duchenne muscular dystrophy. We showed previously that quercetin (Q) partially protected dystrophic limb muscles from disease-related injury. As quercetin activates PGC-1α through Sirtuin-1, an NAD

Indexed as

AnimalsDietary SupplementsDisease Models, AnimalDystrophinMaleMiceMice, Inbred DBAMice, Inbred mdxMuscle ContractionMuscle, SkeletalMuscular Dystrophy, AnimalMuscular Dystrophy, DuchennePharmaceutical PreparationsQuercetinDystrophinPharmaceutical PreparationsQuercetinACE inhibitorDMDglucocorticoidprednisolonequercetin

Identifiers

PMID31295065
PMCPMC7276925
OpenAlexW2962604395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.