Evidence map›Paper›PMID 31294909›Full record

ArticleHuman brain mapping2019

Data-driven model optimization for optically pumped magnetometer sensor arrays.

Leonardo Duque-Muñoz, Tim M Tierney, Sofie S Meyer, Elena Boto, Niall Holmes, Gillian Roberts, James Leggett, J F Vargas-Bonilla, Richard Bowtell, Matthew J Brookes and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. SPM-30 years and beyond.Cerebral cortex (New York, N.Y. : 1991) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. OMMR: Co-registration toolbox of OPM-MEG and MRI.Frontiers in neuroscience · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Leonardo Duque-MuñozSISTEMIC, Engineering Faculty, Universidad de Antioquia UDEA, Calle 70 No 52-51, Medellín, Colombia.ORCID 0000-0001-7115-3870
Tim M TierneyWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, London, UK.
Sofie S MeyerWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, London, UK.
Elena BotoSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.ORCID 0000-0002-0347-280X
Niall HolmesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
Gillian RobertsSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
James LeggettSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
J F Vargas-BonillaSISTEMIC, Engineering Faculty, Universidad de Antioquia UDEA, Calle 70 No 52-51, Medellín, Colombia.
Richard BowtellSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
Matthew J BrookesSir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.ORCID 0000-0002-8687-8185
Jose D LópezSISTEMIC, Engineering Faculty, Universidad de Antioquia UDEA, Calle 70 No 52-51, Medellín, Colombia.ORCID 0000-0003-2213-1186
Gareth R BarnesWellcome Centre for Human Neuroimaging, UCL Institute of Neurology, University College London, London, UK.ORCID 0000-0002-5396-7712
University of Nottingham · GBUniversidad de Antioquia · COWellcome Centre for Human Neuroimaging · GB

Funding

BBSRC research grant BB/M009645/1Departamento Administrativo de Ciencia, Tecnología e Innovación 111577757638Departamento Administrativo de Ciencia, Tecnología e Innovación Convocatoria de Doctorados nacionales 2014Wellcome 203147/Z/16/ZWellcome collaborative award 203257/B/16/ZWellcome collaborative award 203257/Z/16/ZWellcome Trust 203257/Z/16/Z
6 · The paper itself

Abstract

Optically pumped magnetometers (OPMs) have reached sensitivity levels that make them viable portable alternatives to traditional superconducting technology for magnetoencephalography (MEG). OPMs do not require cryogenic cooling and can therefore be placed directly on the scalp surface. Unlike cryogenic systems, based on a well-characterised fixed arrays essentially linear in applied flux, OPM devices, based on different physical principles, present new modelling challenges. Here, we outline an empirical Bayesian framework that can be used to compare between and optimise sensor arrays. We perturb the sensor geometry (via simulation) and with analytic model comparison methods estimate the true sensor geometry. The width of these perturbation curves allows us to compare different MEG systems. We test this technique using simulated and real data from SQUID and OPM recordings using head-casts and scanner-casts. Finally, we show that given knowledge of underlying brain anatomy, it is possible to estimate the true sensor geometry from the OPM data themselves using a model comparison framework. This implies that the requirement for accurate knowledge of the sensor positions and orientations a priori may be relaxed. As this procedure uses the cortical manifold as spatial support there is no co-registration procedure or reliance on scalp landmarks.

Indexed as

Models, TheoreticalAlgorithmsBayes TheoremComputer SimulationElectric StimulationEquipment DesignEvoked Potentials, SomatosensoryHeadHumansLikelihood FunctionsMagnetoencephalographyMagnetometryManikinsMarkov ChainsMedian NerveOptical Devicesbeamformingco-registrationoptically pumped magnetometerssource reconstruction

Identifiers

PMID31294909
PMCPMC6772064
OpenAlexW2959017434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.