Evidence map›Paper›PMID 31294727›Full record

ArticleJournal of the Canadian Association of Gastroenterology2018

Incidence of Suicide in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.

Chaoran Zhang, Glynis Byrne, Terry Lee, Joel Singer, Dean Giustini, Brian Bressler

Open access · goldAbstract readComment
In one paragraph

Article in Journal of the Canadian Association of Gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  11. Addressing Mental Health in Persons with IBD.Journal of the Canadian Association of Gastroenterology · 2018
    Article
  12. Article
  13. Investigating the Relationship Between DNA Methylation, Genetic Variation, and Suicide Attempt in Bipolar Disorder.Archives of suicide research : official journal of the International Academy for Suicide Research
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chaoran ZhangInternal Medicine Residency Training Program, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-0512-3902
Glynis ByrneDepartment of Undergraduate Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Terry LeeCentre for Health Evaluation & Outcome Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Joel SingerCentre for Health Evaluation & Outcome Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Dean GiustiniBiomedical Branch Library, University of British Columbia, Vancouver, British Columbia, Canada.
Brian BresslerDivision of Gastroenterology, University of British Columbia, Vancouver, British Columbia, Canada.
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPatients with inflammatory bowel disease (IBD) have higher incidence of psychosocial disorders, including depression. As suicide is the most severe manifestation of depression, we sought to identify if patients with IBD have a higher incidence of suicide through a systematic review and meta-analysis.

methodsSystematic literature searches for articles using EMBASE and MEDLINE using Ovid were conducted to identify studies investigating suicide in IBD. Reference harvesting of the bibliographies of key articles was also performed. We included studies reporting expected number of death or standardized mortality ratio (SMR) for suicide in IBD. Meta-analysis for each IBD condition (Crohn's disease [CD] and ulcerative colitis [UC]) was conducted separately, as well as combined.

resultsSeven cohort studies were identified through our search strategy and included in our systematic review and meta-analysis. In our analysis, the SMR for suicide in patients with IBD for all studies included was 1.20 (95% CI, 0.94-1.54). The overall pooled SMR for CD and UC were 1.36 (95% CI, 0.98-1.88) and 1.16 (95% CI, 0.8-1.69) respectively.

conclusionsPatients with Crohn's disease and ulcerative colitis may have an increased risk of suicide. These results highlight the importance physicians must place on ensuring the mental health of patients with IBD is both assessed and treated appropriately.

Indexed as

Inflammatory bowel diseaseMeta-analysisSuicideSystematic review

Identifiers

PMID31294727
PMCPMC6507288
OpenAlexW2800217923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.