Evidence map›Paper›PMID 31294391›Full record

ArticleJournal of the Canadian Association of Gastroenterology2018

Clinical Practice Guidelines for the Assessment of Uninvestigated Esophageal Dysphagia.

Louis W C Liu, Christopher N Andrews, David Armstrong, Nicholas Diamant, Nasir Jaffer, Adriana Lazarescu, Marilyn Li, Rosemary Martino, William Paterson, Grigorios I Leontiadis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the Canadian Association of Gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Do Asymptomatic Patients Need Endoscopy after Caustic Ingestion?Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. A case report: cardiac dysphagia-a ghost of the past?European heart journal. Case reports · 2021
    Article
  19. Review
  20. [Approach of Dysphagia].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Louis W C LiuDivision of Gastroenterology, Department of Medicine, University of Toronto, Toronto, ON.
Christopher N AndrewsDivision of Gastroenterology, Department of Medicine, University of Calgary, Calgary, AB.
David ArmstrongDepartment of Medicine, McMaster University, Hamilton, ON.
Nicholas DiamantDivision of Gastroenterology, Department of Medicine, Queen's University, Kingston, ON.
Nasir JafferDepartment of Medical Imaging, Mount Sinai Hospital, Toronto, ON.
Adriana LazarescuDivision of Gastroenterology, University of Alberta, Edmonton, AB.
Marilyn LiDivision of Gastroenterology, Department of Medicine, Queen's University, Kingston, ON.
Rosemary MartinoDepartment of Speech-Language Pathology, University of Toronto, Toronto, ON.
William PatersonDivision of Gastroenterology, Department of Medicine, Queen's University, Kingston, ON.
Grigorios I LeontiadisDepartment of Medicine, McMaster University, Hamilton, ON.
Frances TseDepartment of Medicine, McMaster University, Hamilton, ON.
McMaster University · CAQueen's University · CAUniversity of Toronto · CAMount Sinai Hospital · CAUniversity of Alberta · CAUniversity of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsOur aim is to review the literature and provide guidelines for the assessment of uninvestigated dysphagia.

methodsA systematic literature search identified studies on dysphagia. The quality of evidence and strength of recommendations were rated according to the Grading of Recommendation Assessment, Development, and Evaluation (GRADE) approach. Statements were discussed and revised via small group meetings, teleconferences, and a web-based platform until consensus was reached by the full group.

resultsThe consensus includes 13 statements focused on the role of strategies for the assessment of esophageal dysphagia. In patients presenting with dysphagia, oropharyngeal dysphagia should be identified promptly because of the risk of aspiration. For patients with esophageal dysphagia, history can be used to help differentiate structural from motility disorders and to elicit alarm features. An empiric trial of proton pump inhibitor therapy should be limited to four weeks in patients with esophageal dysphagia who have reflux symptoms and no additional alarm features. For patients with persistent dysphagia, endoscopy, including esophageal biopsy, was recommended over barium esophagram for the assessment of structural and mucosal esophageal disease. Barium esophagram may be useful when the availability of endoscopy is limited. Esophageal manometry was recommended for diagnosis of esophageal motility disorders, and high-resolution was recommended over conventional manometry.

conclusionsOnce oropharyngeal dysphagia is ruled out, patients with symptoms of esophageal dysphagia should be assessed by history and physical examination, followed by endoscopy to identify structural and inflammatory lesions. If these are ruled out, then manometry is recommended for the diagnosis of esophageal dysmotility.

Indexed as

deglutitiongastroesophageal reflux disease (GERD)swallowing

Identifiers

PMID31294391
PMCPMC6487990
OpenAlexW2793439749

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.