ArticleAnnals of maxillofacial surgery
Efficacy of Spirulina along with Different Physiotherapeutic Modalities in the Management of Oral Submucous Fibrosis.
Article in Annals of maxillofacial surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Interventions for managing oral submucous fibrosis.The Cochrane database of systematic reviews · 2024Pooled it
- Comprehensive Review of the Latest Investigations of the Health-Enhancing Effects of Selected Properties ofPharmaceuticals (Basel, Switzerland) · 2024Review
- Cyanobacteria and Microalgae as Sources of Functional Foods to Improve Human General and Oral Health.Molecules (Basel, Switzerland) · 2020Review
- Medicinal management of oral submucous fibrosis in the past decade- A systematic review.Journal of oral biology and craniofacial researchArticle
- Physiotherapy in improving the interincisal mouth opening in oral submucous fibrosis: Meta-analysis.Journal of oral biology and craniofacial researchReview
- Comparative evaluation of spirulina and lycopene as an adjuvant to intralesional corticosteroid injection therapy in the management of oral submucous fibrosis: A pilot study.National journal of maxillofacial surgeryArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextOral submucous fibrosis (OSMF) is an insidious, chronic, disabling disease that mainly affects the oral mucosa. Spirulina is a freshwater microalga which is considered as superfood by the WHO. Due to its antioxidant, anti-inflammatory, and immunomodulating properties, spirulina has shown promising results in the management of OSMF. A wide range of treatment modalities have been tried ranging from medical, physical, or surgical interventions, but combinations of these have shown better results.
aimsThe study aimed to evaluate the efficacy of spirulina along with different physiotherapeutic modalities in the management of OSMF. SETTING AND
designThe present comparative study was conducted in the Department of Oral medicine and radiology, College of Dental Sciences, Davangere, Karnataka, India. The block randomization technique was used in the present study to enroll patients into three different groups.
methodsThe study consisted of 45 OSMF patients who were divided randomly into three groups. All patients were given spirulina 500 mg twice a day for 3 months. Group A patients were instructed to perform isometric mouth exercises for 20 min, twice daily. Group B patients and Group C patients perform exercises using threaded tapered screw and mouth stretching device (MSD), respectively, ten times bilaterally twice a day. Clinical parameters such as burning sensation, mouth opening, tongue protrusion, and cheek flexibility were assessed every 15 days. STATISTICAL ANALYSIS USED: Descriptive data that included mean, numbers, and percentages were calculated for each group and were used for analysis. For intra- and inter-group comparison, paired t- and unpaired RESULTS AND
conclusionAll the groups have shown statistically significant improvement in burning sensation, mouth opening, tongue protrusion, and cheek flexibility (
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