Evidence map›Paper›PMID 31293748›Full record

ArticleChemical science2019

Automated glycan assembly of Lewis type I and II oligosaccharide antigens.

Mónica Guberman, Maria Bräutigam, Peter H Seeberger

Abstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Supramolecular Carbohydrate Assemblies with Tunable Glycan Surfaces.Angewandte Chemie (International ed. in English) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Expediting Glycospace Exploration: Therapeutic Glycans via Automated Synthesis.Angewandte Chemie (International ed. in English) · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. SialylatedJournal of extracellular biology · 2022
    Article
  14. Review
  15. Review
  16. Automated Assembly of Starch and Glycogen Polysaccharides.Journal of the American Chemical Society · 2021
    Article
  17. Microwave-Assisted Automated Glycan Assembly.Journal of the American Chemical Society · 2021
    Article
  18. Automated Glycan Assembly ofAngewandte Chemie (International ed. in English) · 2021
    Article
  19. Article
  20. Enzymatic Building-Block Synthesis for Solid-Phase Automated Glycan Assembly.Angewandte Chemie (International ed. in English) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mónica GubermanDepartment of Biomolecular Systems , Max Planck Institute of Colloids and Interfaces , Am Mühlenberg 1 , 14476 Potsdam , Germany . Email: Peter.Seeberger@mpikg.mpg.de.
Maria BräutigamDepartment of Biomolecular Systems , Max Planck Institute of Colloids and Interfaces , Am Mühlenberg 1 , 14476 Potsdam , Germany . Email: Peter.Seeberger@mpikg.mpg.de.
Peter H SeebergerDepartment of Biomolecular Systems , Max Planck Institute of Colloids and Interfaces , Am Mühlenberg 1 , 14476 Potsdam , Germany . Email: Peter.Seeberger@mpikg.mpg.de.ORCID 0000-0003-3394-8466

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human blood group related glycan antigens are fucosylated (neo-)lactoseries oligosaccharides that play crucial roles in pathogenic processes. Lewis type-II-chain antigens mark the surface of cancer cells, but are also mediators of bacterial infections. To investigate the biological roles of Lewis type glycans a host of synthetic approaches has been developed. Here, we illustrate how automated glycan assembly (AGA) using a set of six monosaccharide building blocks provides quick access to a series of more than ten defined Lewis type-I and type-II antigens, including Le

Identifiers

PMID31293748
PMCPMC6552968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.