Evidence map›Paper›PMID 31293725›Full record

ArticleChemical science2019

PEGylated rhenium nanoclusters: a degradable metal photothermal nanoagent for cancer therapy.

Zhaohua Miao, Sheng Chen, Cheng-Yan Xu, Yan Ma, Haisheng Qian, Yunjun Xu, Huajian Chen, Xianwen Wang, Gang He, Yang Lu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
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  15. Review
  16. Clearable Nanoparticles for Cancer Photothermal Therapy.Advances in experimental medicine and biology · 2021
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhaohua MiaoSchool of Food and Biological Engineering , Hefei University of Technology , Hefei , Anhui 230009 , P. R. China . Email: yanma@hfut.edu.cn ; Email: zbzha@hfut.edu.cn.
Sheng ChenSchool of Chemistry and Chemical Engineering , Hefei University of Technology , Hefei , Anhui 230009 , P. R. China . Email: yanglu@hfut.edu.cn.
Cheng-Yan XuState Key Laboratory of Advanced Welding and Joining , Harbin Institute of Technology , Harbin , 150001 , P. R. China.ORCID 0000-0002-7835-6635
Yan MaSchool of Food and Biological Engineering , Hefei University of Technology , Hefei , Anhui 230009 , P. R. China . Email: yanma@hfut.edu.cn ; Email: zbzha@hfut.edu.cn.
Haisheng QianSchool of Food and Biological Engineering , Hefei University of Technology , Hefei , Anhui 230009 , P. R. China . Email: yanma@hfut.edu.cn ; Email: zbzha@hfut.edu.cn.ORCID 0000-0003-4903-3447
Yunjun XuThe First Affiliated Hospital of University of Science and Technology of China , Anhui Province Hospital , Hefei 230001 , P. R. China.
Huajian ChenSchool of Food and Biological Engineering , Hefei University of Technology , Hefei , Anhui 230009 , P. R. China . Email: yanma@hfut.edu.cn ; Email: zbzha@hfut.edu.cn.
Xianwen WangSchool of Food and Biological Engineering , Hefei University of Technology , Hefei , Anhui 230009 , P. R. China . Email: yanma@hfut.edu.cn ; Email: zbzha@hfut.edu.cn.
Gang HeSchool of Food and Biological Engineering , Hefei University of Technology , Hefei , Anhui 230009 , P. R. China . Email: yanma@hfut.edu.cn ; Email: zbzha@hfut.edu.cn.
Yang LuSchool of Chemistry and Chemical Engineering , Hefei University of Technology , Hefei , Anhui 230009 , P. R. China . Email: yanglu@hfut.edu.cn.ORCID 0000-0002-8412-809X
Qingliang ZhaoState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics , Center for Molecular Imaging and Translational Medicine , School of Public Health , Xiamen University , Xiamen 361102 , China.
Zhengbao ZhaSchool of Food and Biological Engineering , Hefei University of Technology , Hefei , Anhui 230009 , P. R. China . Email: yanma@hfut.edu.cn ; Email: zbzha@hfut.edu.cn.ORCID 0000-0003-3646-4969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A common issue of functional nanoagents for potential clinical translation is whether they are biodegradable or renal clearable. Previous studies have widely explored noble metal nanoparticles (Au and Pd) as the first generation of photothermal nanoagents for cancer therapy, but all of the reported noble metal nanoparticles are non-degradable. On the other hand, rhenium (Re), one of the noble and precious metals with a high atomic number (

Identifiers

PMID31293725
PMCPMC6544121

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.