Evidence map›Paper›PMID 31293565›Full record

ReviewFrontiers in immunology2019

Pruritus in Autoimmune and Inflammatory Dermatoses.

Claudia Zeidler, Manuel Pedro Pereira, Flavien Huet, Laurent Misery, Kerstin Steinbrink, Sonja Ständer

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Rapid improvement of itch with nemolizumab in atopic dermatitis and prurigo nodularis phase 3 studies.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Trial
  3. Article
  4. Immunopathogenesis of itch: an integrative framework for chronic pruritus.JID innovations : skin science from molecules to population health · 2026
    Review
  5. Review
  6. Review
  7. Anti-Inflammatory Evaluation of Pyrazino[2,1-Pharmaceuticals (Basel, Switzerland) · 2026
    Article
  8. Article
  9. International survey of treatment practices for atopic dermatitis in pregnant and breastfeeding women: Physician perspectives.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Article
  10. Article
  11. Skin health and disease · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Frontiers in molecular neuroscience · 2022
    Review
  18. Article
  19. Current Clinical Options for the Management of Itch in Atopic Dermatitis.Clinical, cosmetic and investigational dermatology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Claudia ZeidlerDepartment of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.
Manuel Pedro PereiraDepartment of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.
Flavien HuetDepartment of Dermatology, University Hospital of Brest, Brest, France.
Laurent MiseryDepartment of Dermatology, University Hospital of Brest, Brest, France.
Kerstin SteinbrinkDepartment of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.
Sonja StänderDepartment of Dermatology and Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.
University Hospital Münster · DECentre Hospitalier Régional Universitaire de Brest · FRUniversité de Bretagne Occidentale · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pruritus in autoimmune and inflammatory dermatoses is a common symptom that can be severe and affect the quality of life of patients. In some diseases, pruritus is related to disorders activity and severity or may occur independent of the disease. Despite the high prevalence, the symptom is still underrated and there are only a few trials investigating the efficacy of drugs for disease-specific pruritus. In this review, the characteristics and possible pathomechanisms of pruritus in various dermatoses like autoimmune bullous diseases, connective tissue diseases as well as autoimmune-associated dermatoses (atopic dermatitis, psoriasis vulgaris) is illustrated. Additionally, studies analyzing the antipruritic treatment are discussed. Summarizing, the prevalence of pruritus in these diseases demonstrates the importance for symptom recognition and the need for an efficient antipruritic therapy.

Indexed as

Autoimmune DiseasesDermatitisHumansPruritusSkin Diseasesatopic dermatitisbullous pemphigoidIL31itchprurituspsoriasissubstance P

Identifiers

PMID31293565
PMCPMC6598632
OpenAlexW2949169940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.