Evidence map›Paper›PMID 31293439›Full record

ArticleFrontiers in physiology2019

Effect of Time of Day on Sustained Postexercise Vasodilation Following Small Muscle-Mass Exercise in Humans.

Leandro C Brito, Matthew R Ely, Dylan C Sieck, Joshua E Mangum, Emily A Larson, Christopher T Minson, Cláudia L M Forjaz, John R Halliwill

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Leandro C BritoExercise Hemodynamic Laboratory, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil.
Matthew R ElyDepartment of Human Physiology, University of Oregon, Eugene, OR, United States.
Dylan C SieckDepartment of Human Physiology, University of Oregon, Eugene, OR, United States.
Joshua E MangumDepartment of Human Physiology, University of Oregon, Eugene, OR, United States.
Emily A LarsonDepartment of Human Physiology, University of Oregon, Eugene, OR, United States.
Christopher T MinsonDepartment of Human Physiology, University of Oregon, Eugene, OR, United States.
Cláudia L M ForjazExercise Hemodynamic Laboratory, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil.
John R HalliwillDepartment of Human Physiology, University of Oregon, Eugene, OR, United States.
University of Oregon · USUniversidade de São Paulo · BR

Funding

Exercise, Histamine Receptors, & Vascular Health In AgingR01HL115027 · NHLBI · UNIVERSITY OF OREGON · PI HALLIWILL, JOHN R. · 2013 to 2016
$1.8M
NHLBI NIH HHS R01 HL115027
6 · The paper itself

Abstract

introductionPrevious studies observed diurnal variation in hemodynamic responses during recovery from whole-body exercise, with vasodilation appearing greater after evening versus morning sessions. It is unclear what mechanism(s) underlie this response. Since small muscle-mass exercise can isolate peripheral effects related to postexercise vasodilation, it may provide insight into possible mechanisms behind this diurnal variation.

methodsThe study was conducted in ten healthy (5F, 5M) young individuals, following single-leg dynamic knee-extension exercise performed in the Morning (7:30-11:30 am) or the Evening (5-9 pm) on two different days, in random order. Arterial pressure (automated auscultation) and leg blood flow (femoral artery Doppler ultrasound) were measured pre-exercise and during 120 min postexercise. Net effect for each session was calculated as percent change in blood flow (or vascular conductance) between the Active Leg and the Inactive Leg.

resultsFollowing Morning exercise, blood flow was 34.9 ± 8.9% higher in the Active Leg versus the Inactive Leg (

conclusionThese data suggest previous studies which identified diurnal variations in postexercise vasodilation responses are likely reflecting central rather than peripheral modulation of cardiovascular responses.

Indexed as

aerobic exercisecircadian rhythmdiurnal variationhemodynamicregional blood flow

Identifiers

PMID31293439
PMCPMC6603126
OpenAlexW2954059901

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.