Evidence map›Paper›PMID 31293110›Full record

ArticleJournal of Korean medical science2019

The Effect of Mycophenolate Mofetil on Non-Renal Manifestations in Systemic Lupus Erythematosus: Results from Korean Lupus Network Registry.

Ui Hong Jung, Sang Gyu Kwak, Jung Yoon Choe, Shin Seok Lee, Seong Kyu Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ui Hong JungDivision of Rheumatology, Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-7636-0710
Sang Gyu KwakDepartment of Medical Statistics, Catholic University of Daegu School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0003-0398-5514
Jung Yoon ChoeDivision of Rheumatology, Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0003-0957-0395
Shin Seok LeeDepartment of Rheumatology, Chonnam National University Medical School, Gwangju, Korea.ORCID https://orcid.org/0000-0001-6810-7355
Seong Kyu KimDivision of Rheumatology, Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea. kimsk714@cu.ac.kr.ORCID https://orcid.org/0000-0002-7780-0167
Daegu Catholic University · KRChonnam National University · KR

Funding

Korea Centers for Disease Control & Prevention 2014-E63002-00
6 · The paper itself

Abstract

backgroundThe objective of this study was to identify the effects of mycophenolate mofetil (MMF) on non-renal manifestations in systemic lupus erythematosus (SLE).

methodsThe study population comprised 439 SLE patients from the Korean Lupus Network registry who were followed up annually and completed the baseline survey and two follow-up visits from 2014 to 2018. Disease activity, laboratory markers, and clinical manifestations including mucocutaneous lesions, arthritis, serositis, neurological disorders, and hematologic/immunologic abnormalities were assessed. All variables by group (MMF and non-MMF) effects with time (baseline, 1st follow-up, and 2nd follow-up) were analyzed by generalized estimation equation.

resultsSeventy-two patients were treated with MMF. There was significant difference in frequencies of malar rash, arthritis, renal disorder, and hematologic disorder between MMF and non-MMF groups in total SLE patients. In subgroup analysis of hematologic abnormalities in total patients, frequency of leukopenia was significantly different between the two groups during follow-up (

conclusionThis study showed that MMF might be a beneficial treatment for hematologic abnormalities, especially leukopenia, in SLE.

Indexed as

AdultDepressionExanthemaFemaleHematologic DiseasesHumansLupus Erythematosus, SystemicMaleMiddle AgedMycophenolic AcidQuality of LifeRegistriesRepublic of KoreaMycophenolic AcidMycophenolate MofetilNon-Renal ManifestationsSystemic Lupus Erythematosus

Identifiers

PMID31293110
PMCPMC6624417
OpenAlexW2953634127

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.