Evidence map›Paper›PMID 31293101›Full record

ArticlePhysiological reports2019

TRPM7 is involved in acid-induced necrotic cell death in a manner sensitive to progesterone in human cervical cancer cells.

Tomohiro Numata, Kaori Sato-Numata, Yasunobu Okada

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. The Role of TRPM7 in Oncogenesis.International journal of molecular sciences · 2024
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  6. CaInternational journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Tomohiro NumataDepartment of Physiology, Graduate School of Medical Sciences, Fukuoka University, Fukuoka, Japan.ORCID 0000-0002-5719-4884
Kaori Sato-NumataJapan Society for the Promotion of Science, Tokyo, Japan.
Yasunobu OkadaDepartment of Molecular Cell Physiology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Fukuoka University · JPJapan Society for the Promotion of Science · JPKyoto Prefectural University of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because intravaginal pH is strongly acidic, it is important to investigate the effects of acidosis on cervical cancer cells. Recently, in response to strong acidosis, human cervical cancer HeLa cells were shown to exhibit necrosis after showing persistent cell swelling induced by Cl

Indexed as

ApoptosisCell ProliferationChloridesFemaleHEK293 CellsHeLa CellsHumansHydrogen-Ion ConcentrationNecrosisProgesteroneProtein Serine-Threonine KinasesTRPM Cation ChannelsUterine Cervical NeoplasmsChloridesProgesteroneProtein Serine-Threonine KinasesTRPM7 protein, humanTRPM Cation ChannelsAcidotoxicityapoptosiscervical cancer cellnecrosisprogesteroneTRPM7

Identifiers

PMID31293101
PMCPMC6640595
OpenAlexW2960998248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.