ReviewJournal of diabetes investigation2019
M2-like macrophages serve as a niche for adipocyte progenitors in adipose tissue.
Review in Journal of diabetes investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Defective efferocytosis in diabetes: molecular mechanisms and emerging therapeutic strategies.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Review
- Insulin Resistance and Inflammation.International journal of molecular sciences · 2026Review
- Integrated transcriptomic and functional analyses reveal that NOX2 inhibition rewires the inflammatory landscape of macrophages.Frontiers in immunology · 2026Article
- White Adipocyte Stem Cell Expansion Through Infant Formula Feeding: New Insights into Epigenetic Programming Explaining the Early Protein Hypothesis of Obesity.International journal of molecular sciences · 2025Review
- The role of adipogenic niche resident cells in colorectal cancer progression in relation to obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Review
- The Impact of Resident Adipose Tissue Macrophages on Adipocyte Homeostasis and Dedifferentiation.International journal of molecular sciences · 2024Article
- A Preliminary Study on Factors That Drive Patient Variability in Human Subcutaneous Adipose Tissues.Cells · 2024Article
- Navigating the Adipocyte Precursor Niche: Cell-Cell Interactions, Regulatory Mechanisms and Implications for Adipose Tissue Homeostasis.Journal of cellular signaling · 2024Article
- Generation of functionally active resident macrophages from adipose tissue by 3D cultures.Frontiers in immunology · 2024Article
- Macrophage polarization markers in subcutaneous, pericardial, and epicardial adipose tissue are altered in patients with coronary heart disease.Frontiers in cardiovascular medicine · 2023Article
- Depletion of CD206Nature communications · 2022Article
- Helminth and Host Crosstalk: New Insight Into Treatment of Obesity and Its Associated Metabolic Syndromes.Frontiers in immunology · 2022Review
- TNFα Mediates Inflammation-Induced Effects onCells · 2021Article
- Astaxanthin, a Marine Carotenoid, Maintains the Tolerance and Integrity of Adipose Tissue and Contributes to Its Healthy Functions.Nutrients · 2021Article
- AGMO Inhibitor Reduces 3T3-L1 Adipogenesis.Cells · 2021Article
- Type 2 Innate Lymphoid Cells: Protectors in Type 2 Diabetes.Frontiers in immunology · 2021Review
- BMPR2 promotes fatty acid oxidation and protects white adipocytes from cell death in mice.Communications biology · 2020Article
- M2-like macrophages serve as a niche for adipocyte progenitors in adipose tissue.Journal of diabetes investigation · 2019Review
- Antibacterial and Toxicity Evaluation of Eastern Medicine Formulation Eczegone for the Management of Eczema.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Adipose tissue (AT) is composed not only of adipocytes, but also of macrophages, endothelial cells and preadipocytes. Macrophages are an important component of AT, and are involved in tissue homeostasis, tissue repair and fibrosis. AT-resident macrophages are categorized into two subtypes, the M1-like and M2-like macrophages. M2-like macrophages are reported to play anti-inflammatory roles, and to be involved in clearing and removal of dying/dead adipocytes, and recruiting adipocyte progenitors (APs). M2-like macrophages are also reported to be involved in the promotion of fibrosis in a transforming growth factor-β-dependent manner. However, the precise roles of M2-like macrophages in the AT have not yet been clearly delineated. Recently, we generated genetically engineered transgenic mice in which CD206
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.