Evidence map›Paper›PMID 31292633›Full record

ArticleJournal of the National Cancer Institute2020

Evaluating Screening Participation, Follow-up, and Outcomes for Breast, Cervical, and Colorectal Cancer in the PROSPR Consortium.

William E Barlow, Elisabeth F Beaber, Berta M Geller, Aruna Kamineni, Yingye Zheng, Jennifer S Haas, Chun R Chao, Carolyn M Rutter, Ann G Zauber, Brian L Sprague and 19 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of the National Cancer Institute, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors at 16 institutions in 1 country.

William E BarlowCancer Research and Biostatistics, Seattle, WA.
Elisabeth F BeaberPublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Berta M GellerDepartments of Family Medicine, and the University of Vermont Cancer Center, University of Vermont, Burlington, VT.
Aruna KamineniKaiser Permanente Washington Health Research Institute, Seattle, WA.
Yingye ZhengPublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Jennifer S HaasDivision of General Internal Medicine, Massachusetts General Hospital, Harvard Medical School, Dana Farber, Harvard Cancer Institute, Harvard School of Public Health, Boston, MA.
Chun R ChaoDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA.
Carolyn M RutterRAND Corporation, Santa Monica, CA.
Ann G ZauberDepartment of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Brian L SpragueDepartments of Surgery and Radiology, University of Vermont, Burlington, VT.
Ethan A HalmDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Donald L WeaverDepartment of Pathology and the UVM Cancer Center, University of Vermont, Burlington, VT.
Jessica ChubakKaiser Permanente Washington Health Research Institute, Seattle, WA.
V Paul Doria-RoseDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA.
Sarah KobrinHealthcare Delivery Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD.
Tracy OnegaDepartments of Biomedical Data Science, Epidemiology, and the Dartmouth Institute for Health Policy & Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Virginia P Quinn
Marilyn M SchapiraDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, and CMC VA Medical Center, Philadelphia, PA.
Anna N A TostesonThe Dartmouth Institute for Health Policy and Clinical Practice and Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Douglas A CorleyDivision of Research, Kaiser Permanente Northern California, Oakland, CA.
Celette Sugg SkinnerSimmons Comprehensive Cancer Center, Dallas, TX.
Mitchell D SchnallDepartment of Radiology, University of Pennsylvania, Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA.
Katrina ArmstrongGeneral Medicine Division, MA General Hospital, Harvard Medical School, Boston, MA.
Cosette M WheelerDepartments of Pathology and Obstetrics and Gynecology, University of New Mexico Health Science Center, Albuquerque, NM.
Michael J SilverbergDivision of Research, Kaiser Permanente Northern California, Oakland, CA.
Bijal A BalasubramanianSimmons Comprehensive Cancer Center, Dallas, TX.
Chyke A DoubeniDepartment of Family Medicine and Community Health, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
Dale McLerranPublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Jasmin A TiroSimmons Comprehensive Cancer Center, Dallas, TX.
Kaiser Permanente · USFred Hutch Cancer Center · USHarold C. Simmons Comprehensive Cancer CenterUniversity of Vermont · USDartmouth Institute for Health Policy and Clinical Practice · USHarvard University · USKaiser Permanente Washington Health Research Institute · USMemorial Sloan Kettering Cancer Center · USCancer Research And Biostatistics · USHospital of the University of Pennsylvania · USNational Cancer Institute · USPhiladelphia VA Medical Center · USRAND Corporation · USUniversity of New Mexico · USUniversity of Pennsylvania · USUniversity of Texas Health Science Center at Dallas · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5M
Optimizing the use of colonoscopy for CRC screening in a large community-basedU54CA163262 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CORLEY, DOUGLAS ALLEN, DOUBENI, CHYKE ABADAMA · 2011 to 2017
$9.6M
Parkland-UT Southwestern PROSPR Center Colon Cancer Screening in a Safety netU54CA163308 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI SKINNER, CELETTE SUGG · 2011 to 2017
$8.0M
PROSPR Statistical Coordinating Center (PSCC)U01CA163304 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BARLOW, WILLIAM E, THORNQUIST, MARK · 2011 to 2017
$7.5M
Penn Center for Innovation in Personalized Breast ScreeningU54CA163313 · NCI · UNIVERSITY OF PENNSYLVANIA · PI ARMSTRONG, KATRINA, SCHNALL, MITCHELL D. · 2011 to 2017
$7.4M
Studying Colorectal Cancer Effectiveness of Screening Strategies (SuCCESS)U54CA163261 · NCI · KAISER FOUNDATION RESEARCH INSTITUTE · PI CHUBAK, JESSICA · 2011 to 2017
$7.3M
Vermont Screening Process Documentation UnitU54CA163303 · NCI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SPRAGUE, BRIAN L · 2011 to 2017
$6.4M
Promoting personalized decisions for breast cancer screening for women AND theirU54CA163307 · NCI · DARTMOUTH COLLEGE · PI HAAS, JENNIFER S, ONEGA, TRACY · 2011 to 2017
$6.1M
Patient- and Practice-Centered Assessment of Self-CollectionU54CA164336 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI WHEELER, COSETTE MARIE · 2011 to 2017
$5.5M
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA016086NCI NIH HHS U01 CA163304NCI NIH HHS U54 CA163261NCI NIH HHS U54 CA163262NCI NIH HHS U54 CA163303NCI NIH HHS U54 CA163307NCI NIH HHS U54 CA163308NCI NIH HHS U54 CA163313NCI NIH HHS U54 CA164336
6 · The paper itself

Abstract

backgroundCancer screening is a complex process encompassing risk assessment, the initial screening examination, diagnostic evaluation, and treatment of cancer precursors or early cancers. Metrics that enable comparisons across different screening targets are needed. We present population-based screening metrics for breast, cervical, and colorectal cancers for nine sites participating in the Population-based Research Optimizing Screening through Personalized Regimens consortium.

methodsWe describe how selected metrics map to a trans-organ conceptual model of the screening process. For each cancer type, we calculated calendar year 2013 metrics for the screen-eligible target population (breast: ages 40-74 years; cervical: ages 21-64 years; colorectal: ages 50-75 years). Metrics for screening participation, timely diagnostic evaluation, and diagnosed cancers in the screened and total populations are presented for the total eligible population and stratified by age group and cancer type.

resultsThe overall screening-eligible populations in 2013 were 305 568 participants for breast, 3 160 128 for cervical, and 2 363 922 for colorectal cancer screening. Being up-to-date for testing was common for all three cancer types: breast (63.5%), cervical (84.6%), and colorectal (77.5%). The percentage of abnormal screens ranged from 10.7% for breast, 4.4% for cervical, and 4.5% for colorectal cancer screening. Abnormal breast screens were followed up diagnostically in almost all (96.8%) cases, and cervical and colorectal were similar (76.2% and 76.3%, respectively). Cancer rates per 1000 screens were 5.66, 0.17, and 1.46 for breast, cervical, and colorectal cancer, respectively.

conclusionsComprehensive assessment of metrics by the Population-based Research Optimizing Screening through Personalized Regimens consortium enabled systematic identification of screening process steps in need of improvement. We encourage widespread use of common metrics to allow interventions to be tested across cancer types and health-care settings.

Indexed as

AdultAgedBreast NeoplasmsColorectal NeoplasmsEarly Detection of CancerFemaleFollow-Up StudiesHumansMiddle AgedUnited StatesUterine Cervical NeoplasmsYoung Adult

Identifiers

PMID31292633
PMCPMC7073922
OpenAlexW2959396629

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.