Evidence map›Paper›PMID 31292373›Full record

ArticleInternal medicine (Tokyo, Japan)2019

Elevated Plasma Renin Activity Caused by Accelerated-malignant Hypertension in a Patient with Aldosterone-producing Adenoma Complicated with Renal Insufficiency.

Tatsuya Maruhashi, Michitaka Amioka, Shinji Kishimoto, Hiroki Ikenaga, Kenji Oki, Mari Ishida, Yasuki Kihara, Yukihito Higashi

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Malignant Hypertension and Bilateral Primary Aldosteronism.Internal medicine (Tokyo, Japan) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tatsuya MaruhashiDepartment of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima University, Japan.
Michitaka AmiokaDepartment of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima University, Japan.
Shinji KishimotoDepartment of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan.
Hiroki IkenagaDepartment of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima University, Japan.
Kenji OkiDepartment of Molecular and Internal Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan.
Mari IshidaDepartment of Cardiovascular Physiology and Medicine, Hiroshima University, Japan.
Yasuki KiharaDepartment of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima University, Japan.
Yukihito HigashiDepartment of Cardiovascular Regeneration and Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan.
Hiroshima University · JPHiroshima University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the malignant phase of hypertension in patients with primary aldosteronism complicated with severe renal failure, the plasma renin activity may markedly increase with a false negative screening result for primary aldosteronism, thus potentially leading to a missed diagnosis of primary aldosteronism. We herein report the case of 37-year-old man who presented with accelerated-malignant hypertension complicated with severe renal insufficiency. The plasma renin activity was markedly increased in the malignant phase of hypertension, which were atypical results for primary aldosteronism. However, a plain abdominal computed tomography scan revealed a left adrenal nodule, which was diagnosed as aldosterone-producing adenoma by adrenal venous sampling.

Indexed as

AdenomaAdrenal Cortex NeoplasmsAdultAldosteroneHumansHyperaldosteronismHypertension, MalignantMaleRenal InsufficiencyReninTomography, X-Ray ComputedAldosteroneReninaccelerated-malignant hypertensionplasma aldosterone concentrationplasma renin activityprimary aldosteronism

Identifiers

PMID31292373
PMCPMC6875448
OpenAlexW2957183662

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.