ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2020
Validating an Empirical Mathematical Model for Dynamic Contrast-enhanced MR Imaging of Hand and Wrist Synovitis in Rheumatoid Arthritis: Correlation of Model Parameters with Clinical Disease Activity.
Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Use of DCE-MRI in arthritis in the appendicular skeleton: a narrative review.Skeletal radiology · 2025Review
- Selection of the phase of dynamic contrast-enhanced magnetic resonance imaging and use of the voxel-based enhancement maps may facilitate the assessment of clinical disease activity in patients with rheumatoid arthritis.Japanese journal of radiology · 2025Article
- Anticipations for advancement of non-contrast MRI sequences suitable for longitudinal studies of rheumatoid arthritis.La Radiologia medica · 2023Article
- Dynamic contrast-enhanced MRI could assess the local disease activity of enthesitis and dactylitis in patients with spondyloarthritis.Skeletal radiology · 2023Article
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7 authors.
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Abstract
purposeTo evaluate the feasibility of an empirical mathematical model (EMM) to fit dynamic contrast-enhanced MRI (DCE-MRI) data of hand and wrist synovitis and whether parameters of EMM are significantly correlated with clinical disease activity in patients with rheumatoid arthritis (RA).
methodsThirty-one consecutive patients with RA prospectively underwent Institutional Review Board (IRB)-approved DCE-MRI scans with temporal resolution of 20 s using a 1.5T system. ROIs were placed where the highest signal increase was observed and the kinetic curves were analyzed using an EMM: ΔS(t) = A(1 - e
resultsA showed a significant correlation with DAS28-ESR (r = 0.58; P = 0.0005). β, AUC30 and T
conclusionEMM could fit the DCE-MRI data of hand and wrist synovitis. AUC30 obtained from the uptake phase of the kinetic curve as well as A, β and T
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