ArticleProceedings of the National Academy of Sciences of the United States of America2019
Homeorhesis and ecological succession quantified in synthetic microbial ecosystems.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
- Evolution of phenocopying in a dynamical model of developmental trajectories.PLoS computational biology · 2026Article
- Community First Theory: How Collective Organization Generates Individual Diversity.Entropy (Basel, Switzerland) · 2026Article
- Modeling the zebrafish gut microbiome's resistance and sensitivity to climate change and parasite infection.Frontiers in microbiomes · 2025Article
- Testing the sequence of successional processes in miniature ecosystems.Microbiology spectrum · 2024Article
- Biodiversity and Constrained Information Dynamics in Ecosystems: A Framework for Living Systems.Entropy (Basel, Switzerland) · 2023Article
- Canalisation and plasticity on the developmental manifold of Caenorhabditis elegans.Molecular systems biology · 2023Article
- Shaping bacterial gene expression by physiological and proteome allocation constraints.Nature reviews. Microbiology · 2023Review
- Synthetic symbiosis between a cyanobacterium and a ciliate toward novel chloroplast-like endosymbiosis.Scientific reports · 2023Article
- Calibrating spatiotemporal models of microbial communities to microscopy data: A review.PLoS computational biology · 2022Review
- Evolutionary dynamics, evolutionary forces, and robustness: A nonequilibrium statistical mechanics perspective.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Host Immunity Alters Community Ecology and Stability of the Microbiome in a Caenorhabditis elegans Model.mSystems · 2021Article
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3 authors.
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Abstract
The dynamics of ecological change following a major perturbation, known as succession, are influenced by random processes. Direct quantitation of the degree of contingency in succession requires chronological study of replicate ecosystems. We previously found that population dynamics in carefully controlled, replicated synthetic microbial ecosystems were strongly deterministic over several months. Here, we present simplified, two-species microbial ecosystems consisting of algae and ciliates, imaged in toto at single-cell resolution with fluorescence microscopy over a period of 1 to 2 weeks. To directly study succession in these ecosystems, we deliberately varied the initial cell abundances over replicates and quantified the ensuing dynamics. The distribution of abundance trajectories rapidly converged to a nearly deterministic path, with small fluctuations, despite variations in initial conditions, environmental perturbations, and intrinsic noise, indicative of homeorhesis. Homeorhesis was also observed for certain phenotypic variables, such as partitioning of the ciliates into distinct size classes and clumping of the algae. Although the mechanism of homeorhesis observed in these synthetic ecosystems remains to be elucidated, it is clear that it must emerge from the ways each species controls its own internal states, with respect to a diverse set of environmental conditions and ecological interactions.
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