Evidence map›Paper›PMID 31292114›Full record

ReviewBlood2019

Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia.

Philipp B Staber, Marco Herling, Mar Bellido, Eric D Jacobsen, Matthew S Davids, Tapan Mahendra Kadia, Andrei Shustov, Olivier Tournilhac, Emmanuel Bachy, Francesco Zaja and 9 more

Open access · bronzeAbstract readReviewConsensus Statement
In one paragraph

Review in Blood, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 2 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 2 syntheses or guidelines pooled it, 154 citations in OpenAlex.

  1. Pooled it
  2. Advances and Perspectives in the Treatment of T-PLL.Current hematologic malignancy reports · 2020
    Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. T-prolymphocytic leukemia with three distinct immunophenotypic subsets.Virchows Archiv : an international journal of pathology · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors at 15 institutions in 8 countries.

Philipp B StaberDivision of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-6729-7708
Marco HerlingDepartment of Internal Medicine, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf, and.
Mar BellidoHematology Department, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Eric D JacobsenDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
Matthew S DavidsDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
Tapan Mahendra KadiaDepartment of Leukemia, The University of Texas, MD Anderson Cancer Center, Houston, TX.
Andrei ShustovSeattle Cancer Care Alliance, University of Washington, Seattle, WA.
Olivier TournilhacCentre Hospitalier Universitaire Estaing, Clermont-Ferrand, France.ORCID 0000-0002-9438-621X
Emmanuel BachyDepartment of Hematology, Hospices Civils de Lyon, Lyon, France.
Francesco ZajaS.C. Ematologia Azienda Sanitaria Universitaria Integrata, Trieste, Italy.
Kimmo PorkkaDepartment of Hematology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.ORCID 0000-0003-4112-5902
Gregor HoermannCentral Institute of Medical and Chemical Laboratory Diagnostics, University Hospital Innsbruck, Innsbruck, Austria.
Ingrid Simonitsch-KluppClinical Institute of Pathology, Medical University of Vienna, Vienna, Austria.
Claudia HaferlachMunich Leukemia Laboratory, Munich, Germany.
Stefan KubicekCeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.ORCID 0000-0003-0855-8343
Marius E MayerhoeferDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Georg HopfingerDivision of Blood and Marrow Transplantation, Department of Medicine I, Medical University of Vienna, Vienna, Austria; and.
Ulrich JaegerDivision of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-9826-1062
Claire DeardenThe Royal Marsden Hospital, NHS Foundation Trust, London, United Kingdom.
Medical University of Vienna · ATDana-Farber Cancer Institute · USAustrian Academy of Sciences · ATAzienda Sanitaria Universitaria Integrata di Trieste · ITCentre Hospitalier Universitaire de Clermont-Ferrand · FRHelsinki University Hospital · FIHospices Civils de Lyon · FRMemorial Sloan Kettering Cancer Center · USMunich Leukemia Laboratory (Germany) · DERoyal Marsden NHS Foundation Trust · GBSeattle Cancer Care Alliance · USThe University of Texas MD Anderson Cancer Center · USUniversity Hospital Innsbruck · ATUniversity Medical Center Groningen · NLUniversity of Cologne · DE

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Austrian Science Fund FWF I 4154Austrian Science Fund FWF I 4156NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

T-cell prolymphocytic leukemia (T-PLL) is a rare, mature T-cell neoplasm with a heterogeneous clinical course. With the advent of novel treatment options that will potentially change the management of patients with T-PLL, it has become necessary to produce consensus guidelines for the design and conduct of clinical trials. The T-PLL International Study group (TPLL-ISG) set out to define standardized criteria for diagnosis, treatment indication, and evaluation of response. These criteria will facilitate comparison of results from clinical trials in T-PLL, and will thus support clinical decision making, as well as the approval of new therapeutics by healthcare authorities.

Indexed as

Bone MarrowDisease ManagementGene Expression Regulation, LeukemicHumansImmunophenotypingLeukemia, Prolymphocytic, T-CellMutationNeoplasm StagingT-Lymphocytes

Identifiers

PMID31292114
PMCPMC7042666
OpenAlexW2961584900

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.