Evidence map›Paper›PMID 31292000›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2019

Comparing clinicopathological features and prognosis of primary pulmonary invasive mucinous adenocarcinoma based on computed tomography findings.

Kai Nie, Wei Nie, Yu-Xuan Zhang, Hong Yu

Open access · goldAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Kai NieDepartment of Imaging and Nuclear Medicine, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Wei NieDepartment of Respiration, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, 200030, China.
Yu-Xuan ZhangSchool of pharmacy, Queen's University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, BT9 7BL, Northern Ireland, UK.
Hong YuDepartment of Radiology, Shanghai Chest Hospital, Shanghai Jiaotong University, No.241 Huaihai West Road, Xuhui Area, Shanghai, 200030, China. yuhongphd@163.com.
Shanghai Chest Hospital · CNQueen's University Belfast · GBSecond Military Medical University · CN

Funding

National Natural Science Foundation of China 81601988National Natural Science Foundation of China 81671697Science and Technology Commission of Shanghai Municipality 15411952000Shanghai Shen Kang Hospital Development Center SHDC12014227
6 · The paper itself

Abstract

objectiveTo evaluate the relationship between clinicopathologic characteristics and prognosis in patients with invasive mucinous adenocarcinoma (IMA) of the lung.

methodsA total of 68 patients who underwent surgical resection for primary lung IMA were reviewed during the period of 2009 and 2017. Tumors were classified as solitary-type or pneumonic-type according to the computed tomography (CT) findings. Cox proportional hazards model was used to assess the effects of clinicopathological characteristics on univariate and multivariable analyses of disease-free survival (DFS).

resultsSolitary-type was found in 54 patients, while pneumonic-type was found in 14 patients. The patients' age varied between 56 and 68 years (patients' median age was 61 years). Besides, 50 patients had T1/T2 tumor stage (73.5%). Compared with solitary-type, higher T stage, N stage, and pathological stage (P < 0.001) were found in pneumonic-type. Moreover, the survival analysis showed that the pneumonic-type had a significantly poorer DFS compared with solitary-type (P = 0.004). Univariate analysis showed that pneumonic pattern on CT scan, T stage, pathologic stage, and thyroid transcription factor-1 (TTF-1) were significant predictive factors of survival (P = 0.011, 0.014, 0.013, 0.029, respectively). Multivariate analysis further indicated that pneumonic-type was the only independent prognostic factor for poor survival [hazard ratio (HR) = 6.764, 95% confidence interval (CI): 1.563-29.269, P = 0.011].

conclusionsBased on CT findings, the solitary-type IMA is associated with a lower stage and better prognosis compared with the pneumonic-type IMA.

Indexed as

Adenocarcinoma, MucinousAdenocarcinoma of LungAdultAgedDisease-Free SurvivalFemaleHumansLung NeoplasmsMaleMiddle AgedNeoplasm StagingTomography, X-Ray ComputedComputed tomographyDisease-free survivalInvasive mucinous adenocarcinomaLung cancerPrognosis

Identifiers

PMID31292000
PMCPMC6617846
OpenAlexW2961820213

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.