Evidence map›Paper›PMID 31291944›Full record

ReviewJournal of nanobiotechnology2019

Synthesis and biomedical applications of nanoceria, a redox active nanoparticle.

Neelam Thakur, Prasenjit Manna, Joydeep Das

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed.

  1. A Neutrophil Membrane-Encapsulated Pd/hCeOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  15. The Buffering Activity of Ceria toward Reactive Oxygen Species: A Density Functional Theory Perspective.The journal of physical chemistry. C, Nanomaterials and interfaces · 2025
    Article
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  19. Review
  20. Application and progress of 3D printed biomaterials in osteoporosis.Frontiers in bioengineering and biotechnology · 2025
    Review

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Neelam ThakurSchool of Chemistry, Shoolini University of Biotechnology and Management Sciences, Bajhol, PO Sultanpur, Distt., Solan, 173229, HP, India.
Prasenjit MannaBiological Science and Technology Division, CSIR-North East Institute of Science and Technology, Jorhat, Assam, 785006, India. pmanna2012@gmail.com.
Joydeep DasSchool of Chemistry, Shoolini University of Biotechnology and Management Sciences, Bajhol, PO Sultanpur, Distt., Solan, 173229, HP, India. joydeepdas@shooliniuniversity.com.

Funding

Department of Biotechnology, Govt. of India BT/RLF/Re-Entry/34/2013
6 · The paper itself

Abstract

backgroundNanoceria has recently received much attention, because of its widespread biomedical applications, including antibacterial, antioxidant and anticancer activity, drug/gene delivery systems, anti-diabetic property, and tissue engineering. MAIN BODY: Nanoceria exhibits excellent antibacterial activity against both Gram-positive and Gram-negative bacteria via the generation of reactive oxygen species (ROS). In healthy cells, it acts as an antioxidant by scavenging ROS (at physiological pH). Thus, it protects them, while in cancer cells (under low pH environment) it acts as pro-oxidant by generating ROS and kills them. Nanoceria has also been effectively used as a carrier for targeted drug and gene delivery in vitro and in vivo models. Besides, nanoceria can also act as an antidiabetic agent and confer protection towards diabetes-associated organ pathophysiology via decreasing the ROS level in diabetic subjects. Nanoceria also possesses excellent potential in the field of tissue engineering. In this review, firstly, we have discussed the different methods used for the synthesis of nanoceria as these are very important to control the size, shape and Ce

conclusionThe outcome of this review will improve the understanding about the different synthetic procedures and biomedical applications of nanoceria, which should, in turn, lead to the design of novel clinical interventions associated with various health disorders.

Indexed as

AnimalsAnti-Bacterial AgentsAntineoplastic AgentsAntioxidantsCeriumDrug Delivery SystemsGram-Negative BacteriaGram-Positive BacteriaHumansHypoglycemic AgentsNanoparticlesOxidation-ReductionReactive Oxygen SpeciesTissue EngineeringAnti-Bacterial AgentsAntineoplastic AgentsAntioxidantsceric oxideCeriumHypoglycemic AgentsReactive Oxygen SpeciesAntibacterial activityAnti-cancer activityAnti-diabetic effectAntioxidant activityDrug/gene deliveryNanoceria

Identifiers

PMID31291944
PMCPMC6617741

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.