Evidence map›Paper›PMID 31291936›Full record

ArticleBMC complementary and alternative medicine2019

Virucidal activity of Garcinia parvifolia leaf extracts in animal cell culture.

Aziera Adnan, Zeenathul Nazariah Allaudin, Homayoun Hani, Hwei-San Loh, Teng-Jin Khoo, Kang Nee Ting, Rasedee Abdullah

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Synergistic lipase inhibition by Garcinia parvifolia metabolites: aMetabolomics : Official journal of the Metabolomic Society · 2026
    Article
  2. Antiviral and Cytotoxic Activities ofMolecules (Basel, Switzerland) · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Effect of EthanolicVeterinary sciences · 2021
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Aziera AdnanDepartment of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Zeenathul Nazariah AllaudinDepartment of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. zeenathulnazariah@gmail.com.
Homayoun HaniDepartment of Cell Biology and Physiology, School of Medicine, University North Carolina, Chapel Hill, NC, 27599, USA.
Hwei-San LohSchool of Biosciences, University of Nottingham Malaysia, Jalan Broga, 43500, Semenyih, Selangor, Malaysia.
Teng-Jin KhooSchool of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500, Semenyih, Selangor, Malaysia.
Kang Nee TingSchool of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500, Semenyih, Selangor, Malaysia.
Rasedee AbdullahDepartment of Veterinary Laboratory Diagnostics, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Universiti Putra Malaysia · MYUniversity of Nottingham Malaysia Campus · MYUniversity of North Carolina at Chapel Hill · US

Funding

Ministry of Science and Technology of Malaysia (MOSTI) 03-02-04-0563-SR0008/05-06
6 · The paper itself

Abstract

backgroundGarcinia species contain bioactive compounds such as flavonoids, xanthones, triterpernoids, and benzophenones with antibacterial, antifungal, anti-inflammatory, and antioxidant activities. In addition, many of these compounds show interesting biological properties such as anti-human immunodeficiency virus activity. Garcinia parvifolia is used in traditional medicine. Currently, the antiviral activity of G. parvifolia is not known.

methodsThis study was conducted to determine the effects of ethyl acetate (45 L Ea), ethanol (45 L Et), and hexane (45 L H) leaf extracts of G. parvifolia on the infectivity of pseudorabies virus (PrV) in Vero cells. The antiviral effects of the extracts were determined by cytopathic effect (CPE), inhibition, attachment, and virucidal assays.

resultsThe 50% cytotoxicity concentration (CC

conclusionThis study showed that ethyl acetate is the best solvent to be used to obtain extract from G. parvifolia leaves with potent antiviral activities.

Indexed as

AcetatesAnimalsAntiviral AgentsChlorocebus aethiopsGarciniaHerpesvirus 1, SuidPlant ExtractsVero CellsViral Plaque AssayAcetatesAntiviral Agentsethyl acetatePlant ExtractsCytopathic effect reduction assayEthanolEthyl acetateHexaneInhibition assayPlaque reduction assayPseudorabies virusSelectivity indexVirucidal assay

Identifiers

PMID31291936
PMCPMC6617885
OpenAlexW2958494858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.