ArticleBMC genomics2019
Transcriptome analysis of virulence-differentiated Fusarium oxysporum f. sp. cucumerinum isolates during cucumber colonisation reveals pathogenicity profiles.
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Molecular and Morphological Identification and Pathogenicity ofJournal of fungi (Basel, Switzerland) · 2025Article
- From Morphology to Multi-Omics: A New Age of Fusarium Research.Pathogens (Basel, Switzerland) · 2025Review
- A New Root and Trunk Rot Disease of Grapevine Plantlets Caused byJournal of fungi (Basel, Switzerland) · 2025Article
- FoCup, a secreted protein, is essential for virulence ofFrontiers in microbiology · 2025Article
- Histopathology and quantification of green fluorescent protein-taggedMicrobiology spectrum · 2024Article
- Mechanism of a novelFrontiers in microbiology · 2024Article
- Quantitative Acetylome Analysis of Differentially Modified Proteins in Virulence-DifferentiatedJournal of fungi (Basel, Switzerland) · 2023Article
- Increased Conidia Production and Germination In Vitro Correlate with Virulence Enhancement inJournal of fungi (Basel, Switzerland) · 2023Article
- A broadly conserved fungal alcohol oxidase (AOX) facilitates fungal invasion of plants.Molecular plant pathology · 2023Article
- Serial-Omics and Molecular Function Study Provide Novel Insight into Cucumber Variety Improvement.Plants (Basel, Switzerland) · 2022Review
- Shared and tailored common bean transcriptomic responses to combined fusarium wilt and water deficit.Horticulture research · 2021Article
- Three-Locus Sequence Identification and Differential Tebuconazole Sensitivity Suggest NovelPathogens (Basel, Switzerland) · 2020Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundCucumber Fusarium wilt, caused by Fusarium oxysporum f. sp. cucumerinum (Foc), is one of the most notorious diseases in cucumber production. Our previous research showed the virulence of Foc significantly increases over consecutive rounds of infection in a resistant cultivar. To understand the virulence variation of Foc under host pressure, the mildly virulent strain foc-3b (WT) and its virulence-enhanced variant Ra-4 (InVir) were selected and their transcriptome profiles in infected cucumber roots were analyzed at 24 h after inoculation (hai) and 120 hai.
resultsA series of differentially expressed genes (DEGs) potentially involved in fungal pathogenicity and pathogenicity variation were identified and prove mainly involved in metabolic, transport, oxidation-reduction, cell wall degradation, macromolecules modification, and stress and defense. Among these DEGs, 190 up- and 360 down-regulated genes were expressed in both strains, indicating their importance in Foc infection. Besides, 286 and 366 DEGs showed up-regulated expression, while 492 and 214 showed down-regulated expression in InVir at 24 and 120 hai, respectively. These DEGs may be involved in increased virulence. Notably, transposases were more active in InVir than WT, indicating transposons may contribute to adaptive evolution.
conclusionsBy a comparative transcriptome analysis of the mildly and highly virulent strains of Foc during infection of cucumber, a series of DEGs were identified that may be associated with virulence. Hence, this study provides new insight into the transcriptomic profile underlying pathogenicity and virulence differentiation of Foc.
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