Evidence map›Paper›PMID 31291383›Full record

ArticleMemorias do Instituto Oswaldo Cruz2019

Preliminary assessment of anti-α-Gal IgG and IgM levels in patients with patent Plasmodium vivax infection.

Zélia Barbosa de Almeida Coelho, Luiza Carvalho Mourão, Beatriz Carolina Medeiros Rodrigues, Gustavo Pereira Cardoso-Oliveira, Robert Hincapie, Carlos Sanhueza-Chavez, M G Finn, Cor Jesus Fernandes Fontes, Alexandre Ferreira Marques, Érika Martins Braga

Open access · diamondAbstract read
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Zélia Barbosa de Almeida CoelhoUniversidade Federal de Minas Gerais, Departamento de Parasitologia, Belo Horizonte, MG, Brasil.
Luiza Carvalho MourãoUniversidade Federal de Minas Gerais, Departamento de Parasitologia, Belo Horizonte, MG, Brasil.
Beatriz Carolina Medeiros RodriguesUniversidade Federal de Minas Gerais, Departamento de Parasitologia, Belo Horizonte, MG, Brasil.
Gustavo Pereira Cardoso-OliveiraUniversidade Federal de Minas Gerais, Departamento de Parasitologia, Belo Horizonte, MG, Brasil.
Robert HincapieGeorgia Institute of Technology, School of Chemistry and Biochemistry, Atlanta, GA, USA.
Carlos Sanhueza-ChavezGeorgia Institute of Technology, School of Chemistry and Biochemistry, Atlanta, GA, USA.
M G FinnGeorgia Institute of Technology, School of Chemistry and Biochemistry, Atlanta, GA, USA.
Cor Jesus Fernandes FontesUniversidade Federal do Mato Grosso, Faculdade de Ciências Médicas, Cuiabá, MT, Brasil.
Alexandre Ferreira MarquesUniversidade Federal de Minas Gerais, Departamento de Parasitologia, Belo Horizonte, MG, Brasil.
Érika Martins BragaUniversidade Federal de Minas Gerais, Departamento de Parasitologia, Belo Horizonte, MG, Brasil.ORCID http://orcid.org/0000-0001-5550-7157
Universidade Federal de Minas Gerais · BRGeorgia Institute of Technology · USUniversidade Federal de Mato Grosso · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-α-Gal responses may exert a protective effect in falciparum malaria. However, the biological role of such antibodies is still unknown during Plasmodium vivax infections. We investigated IgG and IgM responses to α-Gal in individuals with vivax malaria. Anti-α-Gal IgG and IgM levels were higher in these patients than in controls, but no significant correlation was found between parasitaemia and anti-α-Gal response, nor between this response and ABO blood group status. This is the first study to investigate anti-α-Gal antibodies in P. vivax-infected patients; a larger survey is necessary to achieve a better understanding of host immune response during vivax malaria.

Indexed as

AdultAntibodies, Anti-IdiotypicHumansImmunoglobulin GImmunoglobulin MMalaria, VivaxMiddle AgedPlasmodium vivaxYoung AdultAntibodies, Anti-Idiotypicanti-IgGImmunoglobulin GImmunoglobulin M

Identifiers

PMID31291383
PMCPMC6611334
OpenAlexW2954298054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.