Evidence map›Paper›PMID 31291362›Full record

ArticlePloS one2019

Sequence and phylogenetic analysis of novel porcine parvovirus 7 isolates from pigs in Guangxi, China.

Wei Wang, Liang Cao, Wenchao Sun, Jialiang Xin, Min Zheng, Mingyao Tian, Huijun Lu, Ningyi Jin

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Wei WangCollege of Animal Science and Technology, Guangxi University, Nanning, People's Republic of China.
Liang CaoInstitute of Military Veterinary, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Academy of Military Sciences, Changchun, People's Republic of China.
Wenchao SunInstitute of Military Veterinary, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Academy of Military Sciences, Changchun, People's Republic of China.
Jialiang XinCollege of Animal Science and Technology, Guangxi University, Nanning, People's Republic of China.
Min ZhengGuangxi Center for Animal Disease Control and Prevention, Nanning, People's Republic of China.
Mingyao TianInstitute of Military Veterinary, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Academy of Military Sciences, Changchun, People's Republic of China.
Huijun LuInstitute of Military Veterinary, Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Academy of Military Sciences, Changchun, People's Republic of China.
Ningyi JinCollege of Animal Science and Technology, Guangxi University, Nanning, People's Republic of China.ORCID 0000-0002-1959-4465
Academy of Military Medical Sciences · CNGuangxi University · CNWenzhou University · CNGuangxi Center for Disease Prevention and Control · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parvoviruses are a diverse group of viruses that infect a wide range of animals and humans. In recent years, advances in molecular techniques have resulted in the identification of several novel parvoviruses in swine. In this study, porcine parvovirus 7 (PPV7) isolates from clinical samples collected in Guangxi, China, were examined to understand their molecular epidemiology and co-infection with porcine circovirus type 2 (PCV2). In this study, among the 385 pig serum samples, 105 were positive for PPV7, representing a 27.3% positive detection rate. The co-infection rate of PPV7 and PCV2 was 17.4% (67/385). Compared with the reference strains, we noted 93.9%-97.9% similarity in the NS1 gene and 87.4%-95.0% similarity in the cap gene. Interestingly, compared with the reference strains, sixteen of the PPV7 strains in this study contained an additional 3 to 15 nucleotides in the middle of the cap gene. Therefore, the Cap protein of fourteen strains encoded 474 amino acids, and the Cap protein of the other two strains encoded 470 amino acids. However, the Cap protein of the reference strain PPV7 isolate 42 encodes 469 amino acids. This is the first report of sequence variation within the cap gene, confirming an increase in the number of amino acids in the Cap protein of PPV7. Our findings provide new insight into the prevalence of PPV7 in swine in Guangxi, China, as well as sequence data and phylogenetic analysis of these novel PPV7 isolates.

Indexed as

AnimalsChinaCircoviridae InfectionsCircovirusCoinfectionGenes, ViralGenetic VariationMolecular EpidemiologyParvoviridae InfectionsParvovirus, PorcinePhylogenyPrevalenceSus scrofaSwineSwine Diseases

Identifiers

PMID31291362
PMCPMC6619813
OpenAlexW2961100183

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.