Evidence map›Paper›PMID 31291330›Full record

Trial reportPloS one2019

Economic evaluation of a childhood obesity prevention programme for children: Results from the WAVES cluster randomised controlled trial conducted in schools.

Alastair Canaway, Emma Frew, Emma Lancashire, Miranda Pallan, Karla Hemming, Peymane Adab, WAVES trial investigators

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 5 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 5 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Interventions to prevent obesity in children aged 5 to 11 years old.The Cochrane database of systematic reviews · 2024
    Pooled it
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  6. Trial
  7. Pharmacoeconomic evaluation of treatments for Poly Cystic Ovarian Syndrome (PCOS).Cost effectiveness and resource allocation : C/E · 2024
    Article
  8. Review
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  10. Article
  11. Modeling Obesity in Norway (The MOON Study): A Decision-Analytic Approach-Prevalence, Costs, and Years of Life Lost.Medical decision making : an international journal of the Society for Medical Decision Making · 2021
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alastair CanawayInstitute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Emma FrewInstitute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0002-5462-1158
Emma LancashireInstitute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Miranda PallanInstitute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Karla HemmingInstitute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Peymane AdabInstitute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
WAVES trial investigators
University of Birmingham · GB

Funding

Department of Health 06/85/11Department of Health SRF-2017-10-002
6 · The paper itself

Abstract

backgroundChildhood obesity is a serious public health challenge and schools have been identified as an ideal place to implement prevention interventions. The aim of this study was to measure the cost-effectiveness of a multi-faceted school-based obesity prevention intervention targeting children aged 6-7 years when compared to 'usual activities'.

methodsA cluster randomised controlled trial in 54 schools across the West Midlands (UK) was conducted. The 12-month intervention aimed to increase physical activity by 30 minutes per day and encourage healthy eating. Costs were captured from a public sector perspective and utility-based health related outcomes measured using the CHU-9D. Multiple imputation using chained equations was used to address missing data. The cost effectiveness was measured at 30 months from baseline using a hierarchical net-benefit regression framework, that controlled for clustering and prespecified covariates. Any uncertainty in the results was characterised using cost-effectiveness acceptability curves.

resultsAt 30 months, the total adjusted incremental mean cost of the intervention was £155 (95% confidence interval [CI]: £139, £171), and the incremental mean QALYs gained was 0.006 (95% CI: -0.024, 0.036), per child. The incremental cost-effectiveness at 30 months was £26,815 per QALY and using a standard willingness to pay threshold of £30,000 per QALY, there was a 52% chance that the intervention was cost-effective.

conclusionsThe cost-effectiveness of the school-based WAVES intervention was subject to substantial uncertainty. We therefore recommend more research to explore obesity prevention within schools as part of a wider systems approach to obesity prevention.

trial registrationThis paper uses data collected by the WAVES trial: Controlled trials ISRCTN97000586 (registered May 2010).

Indexed as

Cost-Benefit AnalysisBody Mass IndexChildDiet, HealthyExerciseFemaleHealth PromotionHumansMaleOutcome Assessment, Health CarePediatric ObesityQuality-Adjusted Life YearsSchool Health ServicesUncertaintyUnited Kingdom

Identifiers

PMID31291330
PMCPMC6619792
OpenAlexW2961665918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.