ArticlePloS one2019
Factors associated with poor adherence to medication among hypertensive patients in twelve low and middle income Sub-Saharan countries.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 3 of them syntheses that pooled it.
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Who cites it
69 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Assessing implementation outcomes from studies addressing medication adherence for hypertension management in Sub-Saharan Africa: a systematic review.BMC public health · 2025Pooled it
- High Burden and Trend in Nonadherence to Blood Pressure-Lowering Medications: Meta-Analysis of Data From Over 34 000 Adults With Hypertension in Sub-Saharan Africa.Journal of the American Heart Association · 2025Pooled it
- Global Burden, Regional Differences, Trends, and Health Consequences of Medication Nonadherence for Hypertension During 2010 to 2020: A Meta-Analysis Involving 27 Million Patients.Journal of the American Heart Association · 2022Pooled it
- Article
- Optimising care for uncomplicated type 2 diabetes mellitus in Lagos, Nigeria: cost and benefit estimates using real-world data.BMJ global health · 2026Article
- "medRxiv : the preprint server for health sciences · 2026Article
- Psychological distress and its influence on medication adherence among patients with co-morbid hypertension and diabetes: an explanatory sequential mixed-methods study.BMC public health · 2026Article
- Antihypertensive medication adherence and associated risk factors among adults with hypertension: a cross-sectional study in a teaching hospital, Ghana.BMC cardiovascular disorders · 2026Article
- Medication Adherence Among Hypertensive Patients in Bangladesh: A Nationwide Analysis of Gender and Urban-Rural Disparities.International journal of hypertension · 2026Article
- WhatsApp and YouTube as platforms for facilitating lifestyle modifications among individuals with hypertension in a low-income, urban community in Karachi, Pakistan: a qualitative study.BMJ public health · 2026Article
- Therapeutic Adherence in Cardiovascular Diseases: Insights from the Patient and Physician-A Narrative Review.Advances in therapy · 2026Review
- Prevalence, Awareness, and Treatment of Hypertension in 37 African Countries: Trends From 2003 to 2022.Journal of the American College of Cardiology · 2025Article
- A comprehensive global review on pharmacist-led strategies to support medication therapy in hypertensive patients.Journal of human hypertension · 2025Review
- Use of traditional medicine for hypertension, diabetes and hypercholesterolaemia measured in 71 surveys.Bulletin of the World Health Organization · 2025Article
- Adherence to hypertension management at a rural hospital in Limpopo: A cross-sectional study.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025Article
- Prevalence and associated factors of adherence to antihypertensive medication: a nationwide cross-sectional study.BMC public health · 2025Article
- Factors affecting adherence to hypertension medications in hypertensive patients attending to primary health care units in Bahrain.Journal of family medicine and primary care · 2025Article
- Left ventricular hypertrophy among adults in a population-based cohort in Haiti.Scientific reports · 2025Article
- SPIRITUALITY AND MEDICATION ADHERENCE AMONG HYPERTENSIVES ATTENDING THE FAMILY MEDICINE CLINIC OF A NIGERIAN TERTIARY INSTITUTION: ANY MEETING POINT?Annals of Ibadan postgraduate medicine · 2025Article
- Worldwide study of the taste of bitter medicines and their modifiers.Chemical senses · 2025Article
9 more citing papers are in PubMed but not listed here.
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25 authors.
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Abstract
introductionOver the past few decades, the prevalence of hypertension has dramatically increased in Sub-Saharan Africa. Poor adherence has been identified as a major cause of failure to control hypertension. Scarce data are available in Africa.
aimsWe assessed adherence to medication and identified socioeconomics, clinical and treatment factors associated with low adherence among hypertensive patients in 12 sub-Saharan African countries.
methodWe conducted a cross-sectional survey in urban clinics of both low and middle income countries. Data were collected by physicians on demographics, treatment and clinical data among hypertensive patients attending the clinics. Adherence was assessed by questionnaires completed by the patients. Factors associated with low adherence were investigated using logistic regression with a random effect on countries.
resultsThere were 2198 individuals from 12 countries enrolled in the study. Overall, 678 (30.8%), 738 (33.6%), 782 (35.6%) participants had respectively low, medium and high adherence to antihypertensive medication. Multivariate analysis showed that the use of traditional medicine (OR: 2.28, 95%CI [1.79-2.90]) and individual wealth index (low vs. high wealth: OR: 1.86, 95%CI [1.35-2.56] and middle vs. high wealth: OR: 1.42, 95%CI [1.11-1.81]) were significantly and independently associated with poor adherence to medication. In stratified analysis, these differences in adherence to medication according to individual wealth index were observed in low-income countries (p<0.001) but not in middle-income countries (p = 0.17). In addition, 26.5% of the patients admitted having stopped their treatment due to financial reasons and this proportion was 4 fold higher in the lowest than highest wealth group (47.8% vs 11.4%) (p<0.001).
conclusionThis study revealed the high frequency of poor adherence in African patients and the associated factors. These findings should be useful for tailoring future programs to tackle hypertension in low income countries that are better adapted to patients, with a potential associated enhancement of their effectiveness.
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