ArticlePloS one2019
HCV screening, linkage to care, and treatment patterns at different sites across one academic medical center.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Characteristics and Outcomes of Direct-Acting Antiviral Experienced Patients with Hepatitis C Undergoing Retreatment at an Essential Hospital in the United States.Open forum infectious diseases · 2024Trial
- Trial
- Development and Validation of a Machine Learning-Based Screening Algorithm to Predict High-Risk Hepatitis C Infection.Open forum infectious diseases · 2025Article
- Barriers to recruitment of an observational SARS-CoV-2 emergency department cohort at Boston Medical Center.BMC emergency medicine · 2025Observational
- Validating an Electronic Health Record Algorithm for Diabetes Screening Eligibility in the Emergency Department.The western journal of emergency medicine · 2025Article
- Enhancing Hepatitis C Virus Testing, Linkage to Care, and Treatment Commencement in Hospitals: A Systematic Review and Meta-analysis.Open forum infectious diseases · 2025Article
- Article
- A Potential Screening Strategy to Identify Probable Syphilis Infections in the Urban Emergency Department Setting.Open forum infectious diseases · 2024Article
- No Patient Left Behind: A Novel Paradigm to Fulfill Hepatitis C Virus Treatment for Rural Patients.Open forum infectious diseases · 2024Article
- Using Community Paramedicine to Treat Hepatitis C Virus in Upstate South Carolina.Southern medical journal · 2023Article
- Article
- Evaluation of a pilot emergency department linkage to care program for patients previously diagnosed with Hepatitis C.Journal of viral hepatitis · 2023Article
- Early cost-utility analysis of hepatitis C virus testing for emergency department attendees in France.PLOS global public health · 2023Article
- Impact of an interdisciplinary patient care model and routine screening on clinical outcomes in patients with hepatitis C.Innovations in pharmacy · 2023Article
- Projected Long-Term Impact of the Coronavirus Disease 2019 (COVID-19) Pandemic on Hepatitis C Outcomes in the United States: A Modeling Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Treating the Hardest to Treat: Reframing the Hospital Admission as an Opportunity to Initiate Hepatitis C Treatment.Digestive diseases and sciences · 2022Article
- Hepatitis C Virus Reflex Testing Protocol in an Emergency Department.The western journal of emergency medicine · 2022Article
- Article
- Effect of relaxing hepatitis C treatment restrictions on direct-acting antiviral use in a Medicaid program: an interrupted time series analysis.Journal of managed care & specialty pharmacy · 2021Article
- The performance of hepatitis C virus (HCV) antibody point-of-care tests on oral fluid or whole blood and dried blood spot testing for HCV serology and viral load among individuals at higher risk for HCV in South Africa.Health science reports · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt is unclear whether sites that screen large numbers of patients for Hepatitis C Virus but achieve limited follow-up are more or less effective at having patients succeed through linkage and treatment than lower volume sites that have higher linkage percentages. The objective was to compare the rates of HCV identification, linkage to care, and treatment success between different study sites including the Emergency Department, 3 outpatient clinics with unique patients, and the inpatient setting at one medical center.
methodsThis is a descriptive analysis of 2 years of data from a protocol that integrated HCV screening and treatment into clinical services throughout multiple departments in one medical center. The program used a best practice advisory to prompt testing at all sites, with different triggers for it to fire at each site, and one central navigation program that attempted to link all patients diagnosed with hepatitis C virus to outpatient care. Outcomes included volume of tests performed in each site, Antibody and RNA rates at each site, demographic data, navigation and linkage outcomes, and post-linkage treatment completion.
results28,435 patients were screened across 5 clinical locations. RNA+ rates and absolute numbers linked to MD (linkage rates among all RNA+) were: ED 7.2% RNA+, 224 (22.6%) linked; Inpatient 14.8% RNA+, 27 (17.6%) linked, General Internal Medicine 3.9% RNA+, 269 (65.8%) linked, Infectious Diseases 4.0% RNA+, 34(70.8%) linked, Family Medicine 2.0% RNA+, 28 (75.7%) linked. Demographics, linkage barriers, and treatment initiation rates were different at all sites.
conclusionAmong sites there were differences in the sociodemographic characteristics of patients diagnosed with HCV, as well as differences in the success linking patients to outpatient care. At this medical center, the ED screened the most patients, the inpatient area had the highest RNA positivity rate, the FM clinic had the highest linkage rate, GIM linked the most patients by absolute number, and GIM also had the highest number of patients start treatment.
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