ArticleRadiation research2019
Radiation and Risk of Liver, Biliary Tract, and Pancreatic Cancers among Atomic Bomb Survivors in Hiroshima and Nagasaki: 1958-2009.
Article in Radiation research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 43 citations in OpenAlex.
- Eight decades of research on the long-term health effects of radiation in atomic bomb survivors and their offspring.Carcinogenesis · 2025Review
- Summary of radiation effects on incidence of solid cancers in the Life Span Study of atomic bomb survivors: 1958-2009.Carcinogenesis · 2025Article
- The importance of data from the atomic bomb survivors for international radiological protection.Carcinogenesis · 2025Article
- Trans-Scale Insights into Variability in Radiation Cancer Risk Across Tissues, Individuals, and Species.Biology · 2025Review
- Establishment and activity of the planning and acting network for low dose radiation research in Japan (PLANET): 2016-2023.Journal of radiation research · 2024Article
- A Historical Survey of Key Epidemiological Studies of Ionizing Radiation Exposure.Radiation research · 2024Review
- Incidence risk of hepatobiliary malignant neoplasms in the cohort of workers chronically exposed to ionizing radiation.Scientific reports · 2024Article
- Comparison of All Solid Cancer Mortality and Incidence Dose-Response in the Life Span Study of Atomic Bomb Survivors, 1958-2009.Radiation research · 2022Article
- Race and ethnic group dependent space radiation cancer risk predictions.Scientific reports · 2022Article
- Radiation concerns in frequent flyer patients: should imaging history influence decisions about recurrent imaging?The British journal of radiology · 2021Review
- Misclassification of primary liver cancer in the Life Span Study of atomic bomb survivors.International journal of cancer · 2020Article
- High CT doses return to the agenda.Radiation and environmental biophysics · 2020Article
- Article
- Radiophobia Harm, Its Main Cause, and a Proposed Solution.Dose-response : a publication of International Hormesis SocietyArticle
- Impact of a Short-Term High-Fat Diet on Lifespan and Tumorigenesis After Early-Life Exposure to Radiation.Dose-response : a publication of International Hormesis SocietyArticle
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
The Life Span Study (LSS) of atomic bomb survivors has consistently demonstrated significant excess radiation-related risks of liver cancer since the first cancer incidence report. Here, we present updated information on radiation risks of liver, biliary tract and pancreatic cancers based on 11 additional years of follow-up since the last report, from 1958 to 2009. The current analyses used improved individual radiation doses and accounted for the effects of alcohol consumption, smoking and body mass index. The study participants included 105,444 LSS participants with known individual radiation dose and no known history of cancer at the start of follow-up. Cases were the first primary incident cancers of the liver (including intrahepatic bile duct), biliary tract (gallbladder and other and unspecified parts of biliary tract) or pancreas identified through linkage with population-based cancer registries in Hiroshima and Nagasaki. Poisson regression methods were used to estimate excess relative risks (ERRs) and excess absolute risks (EARs) associated with DS02R1 doses for liver (liver and biliary tract cancers) or pancreas (pancreatic cancer). We identified 2,016 incident liver cancer cases during the follow-up period. Radiation dose was significantly associated with liver cancer risk (ERR per Gy: 0.53, 95% CI: 0.23 to 0.89; EAR per 10,000 person-year Gy: 5.32, 95% CI: 2.49 to 8.51). There was no evidence for curvature in the radiation dose response (
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