Evidence map›Paper›PMID 31291042›Full record

ArticleThe American journal on addictions2019

Risk Factors for Overdose in Young People Who Received Substance Use Disorder Treatment.

Amy M Yule, Nicholas W Carrellas, Maura DiSalvo, Rachael M Lyons, James W McKowen, Jessica E Nargiso, Brandon G Bergman, John F Kelly, Timothy E Wilens

Open access · greenAbstract read
In one paragraph

Article in The American journal on addictions, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Amy M YulePediatric Psychopharmacology Program, Division of Child Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.ORCID 0000-0002-2409-9426
Nicholas W CarrellasPediatric Psychopharmacology Program, Division of Child Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Maura DiSalvoPediatric Psychopharmacology Program, Division of Child Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Rachael M LyonsPediatric Psychopharmacology Program, Division of Child Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
James W McKowenAddiction Recovery Management Service, Center for Addiction Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Jessica E NargisoAddiction Recovery Management Service, Center for Addiction Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Brandon G BergmanAddiction Recovery Management Service, Center for Addiction Medicine, Massachusetts General Hospital, Boston, Massachusetts.
John F KellyAddiction Recovery Management Service, Center for Addiction Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Timothy E WilensPediatric Psychopharmacology Program, Division of Child Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Harvard University · USMassachusetts General Hospital · US

Funding

AACAP Physician Scientist Program in Substance UseK12DA000357 · NIDA · AMERICAN ACADEMY-CHILD/ADOLESCENT PSYCH · PI Kevin M. Gray · 1998 to 2026
$29.1M
Funded extension request for "Expanding recovery support for emerging adults with alcohol use disorder: Training in the science of social network sites"K23AA025707 · NIAAA · MASSACHUSETTS GENERAL HOSPITAL · PI BERGMAN, BRANDON G. · 2018 to 2023
$1.0M
American Academy of Child and Adolescent Psychiatry Physician Scientist in Substance Abuse Award K12DA000357-17Massachusetts General Hospital Louis V. Gerstner III Research Scholar AwardNIAAA NIH HHS K23 AA025707NIDA NIH HHS K12 DA000357
6 · The paper itself

Abstract

BACKGROUND AND

objectivesTo identify substance and psychiatric predictors of overdose (OD) in young people with substance use disorders (SUDs) who received treatment.

methodsWe conducted a retrospective review of consecutive medical records of young people who were evaluated in a SUD program between 2012 and 2013 and received treatment. An independent group of patients from the same program who received treatment and had a fatal OD were also included in the sample. OD was defined as substance use associated with a significant impairment in level of consciousness without intention of self-harm, or an ingestion of a substance that was reported as a suicide attempt. t Tests, Pearson's χ

resultsAfter initial evaluation, 127 out of 200 patients followed up for treatment and were included in the sample. Ten (8%) of these patients had a nonfatal OD. Nine patients who received treatment and had a fatal OD were also identified. The sample's mean age was 20.2 ± 2.8 years. Compared with those without OD, those with OD were more likely to have a history of intravenous drug use (odds ratio [OR]: 36.5, P < .001) and mood disorder not otherwise specified (OR: 4.51, P = .01). DISCUSSION AND

conclusionsIntravenous drug use and mood dysregulation increased risk for OD in young people who received SUD treatment. SCIENTIFIC SIGNIFICANCE: It is important to identify clinically relevant risk factors for OD specific to young people in SUD treatment due to the risk for death associated with OD. (Am J Addict 2019;28:382-389).

Indexed as

AdolescentAdultDrug OverdoseFemaleHumansMaleMood DisordersRetrospective StudiesRisk FactorsSubstance Abuse, IntravenousSubstance-Related DisordersSuicide, AttemptedYoung Adult

Identifiers

PMID31291042
PMCPMC6706285
OpenAlexW2958110206

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.