Evidence map›Paper›PMID 31290748›Full record

ArticleThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2019

Association of obesity with chronic kidney disease in elderly patients with nonalcoholic fatty liver disease.

Kexue Luo, Jie Bian, Qinxian Wang, Jiesheng Wang, Fuxing Chen, Hongchun Li, Dong Jin

Open access · bronzeAbstract read
In one paragraph

Article in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kexue LuoTongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Jie BianSir Run Run Shaw Hospital, International Medical Center, Zhejiang University, Zhejiang, China.
Qinxian WangTongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Jiesheng WangTongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Fuxing ChenTongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Hongchun LiTongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Dong JinTongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Tongde Hospital of Zhejiang Province · CNSir Run Run Shaw Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThis study investigated an association between obesity and impaired renal functions in elderly patients with nonalcoholic fatty liver disease (NAFLD) and evaluated the risk factors for chronic kidney disease (CKD) in these patients. MATERIALS AND

methodsA cross-sectional study was performed involving 515 elderly patients (≥ 60 years old) with NAFLD. Demographics, body mass index (BMI), medical history, and laboratory parameters were compared for groups stratified by obesity (≥ 28 kg/m2) or CKD. An association between obesity and CKD was analyzed, and a multivariate logistic regression analysis was conducted for risk factors associated with CKD.

resultsIn the overall population, 28.7% were obese and 54.8% had CKD; there were more women (58.8%) than men. The prevalence of hypertension and diabetes was similar between the obese and nonobese groups and between the CKD and non-CKD groups. Obese patients had significantly higher levels of serum uric acid and estimated glomerular filtration rates when compared with the nonobese group. When compared with those without CKD, patients with CKD were significantly older in addition to having higher BMI and serum uric acid levels. The multivariate logistic regression analysis indicated that CKD was positively associated with age, BMI, and serum uric acid levels.

conclusionElderly obese patients with NAFLD are at a higher risk of CKD. NAFLD patients with advanced age, greater BMI, or higher serum uric acid levels are more prone to developing CKD. The renal function of NAFLD patients should be closely monitored.

Indexed as

AgedAge FactorsBiomarkersBody Mass IndexCross-Sectional StudiesFemaleHumansKidney Function TestsMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseObesityRenal Insufficiency, ChronicRisk FactorsSex FactorsUric AcidBiomarkersUric Acid

Identifiers

PMID31290748
PMCPMC6629282
OpenAlexW2919814416

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.