Evidence map›Paper›PMID 31290708›Full record

ArticleDrug delivery2019

Development of synthetic high-density lipoprotein-based ApoA-I mimetic peptide-loaded docetaxel as a drug delivery nanocarrier for breast cancer chemotherapy.

Miaomiao Gong, Qi Zhang, Qi Zhao, Jiani Zheng, Yue Li, Siling Wang, Yue Yuan

Open access · goldAbstract read
In one paragraph

Article in Drug delivery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Apolipoproteins: New players in cancers.Frontiers in pharmacology · 2022
    Review
  6. HDL and Therapy.Advances in experimental medicine and biology · 2022
    Article
  7. Apolipoprotein mimetics in cancer.Seminars in cancer biology · 2021
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Miaomiao Gonga School of Pharmacy , Shenyang Pharmaceutical University , Shenyang , P. R. China.
Qi Zhangc Department of General Surgery , General Hospital of Benxi Iron and Steel Co. Ltd , Benxi , P. R. China.
Qi Zhaoa School of Pharmacy , Shenyang Pharmaceutical University , Shenyang , P. R. China.
Jiani Zhenga School of Pharmacy , Shenyang Pharmaceutical University , Shenyang , P. R. China.
Yue Lia School of Pharmacy , Shenyang Pharmaceutical University , Shenyang , P. R. China.
Siling Wanga School of Pharmacy , Shenyang Pharmaceutical University , Shenyang , P. R. China.
Yue Yuana School of Pharmacy , Shenyang Pharmaceutical University , Shenyang , P. R. China.
Shenyang Pharmaceutical University · CNTaiyuan Iron and Steel Group (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a synthetic high-density lipoprotein (sHDL), peptide-based nanocarrier loaded with docetaxel (DTX) was constructed, against breast cancer. The thermodynamic and molecular dynamic analyses were conducted to examine the stability of nanoparticles synthesized from mimetic peptide 5 A and various types of phospholipids. Furthermore, the cellular uptake and

Indexed as

AnimalsAntineoplastic AgentsApolipoprotein A-IBiomimetic MaterialsDelayed-Action PreparationsDocetaxelDrug CarriersEpithelial CellsFemaleHumansMammary Neoplasms, ExperimentalMCF-7 CellsMiceNanoparticlesOptical ImagingPeptidesAntineoplastic AgentsApolipoprotein A-IDelayed-Action PreparationsDocetaxelDrug CarriersPeptidesSCARB1 protein, humanScavenger Receptors, Class Banticancerbreast cancerdocetaxelmimetic peptideSynthetic high-density lipoprotein

Identifiers

PMID31290708
PMCPMC6691925
OpenAlexW2961316906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.