Evidence map›Paper›PMID 31290284›Full record

ArticlePediatric obesity2019

Brown adipose tissue estimated with the magnetic resonance imaging fat fraction is associated with glucose metabolism in adolescents.

Elin Lundström, Joy Ljungberg, Jonathan Andersson, Hannes Manell, Robin Strand, Anders Forslund, Peter Bergsten, Daniel Weghuber, Katharina Mörwald, Fanni Zsoldos and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Pediatric obesity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. International journal of molecular sciences · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elin LundströmDepartment of Surgical Sciences, Section of Radiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-2955-4958
Joy LjungbergDepartment of Surgical Sciences, Section of Radiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-6209-591X
Jonathan AnderssonDepartment of Surgical Sciences, Section of Radiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-6477-2331
Hannes ManellDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-5209-4841
Robin StrandDepartment of Surgical Sciences, Section of Radiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-7764-1787
Anders ForslundDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-9109-4556
Peter BergstenDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-4937-8464
Daniel WeghuberDepartment of Pediatrics, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0002-4389-0379
Katharina MörwaldDepartment of Pediatrics, Paracelsus Medical University, Salzburg, Austria.
Fanni ZsoldosDepartment of Pediatrics, Paracelsus Medical University, Salzburg, Austria.
Kurt WidhalmDepartment of Pediatrics, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0001-8700-5573
Matthias MeissnitzerDepartment of Radiology, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0003-2422-8838
Håkan AhlströmDepartment of Surgical Sciences, Section of Radiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-8701-969X
Joel KullbergDepartment of Surgical Sciences, Section of Radiology, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-8205-7569

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite therapeutic potential against obesity and diabetes, the associations of brown adipose tissue (BAT) with glucose metabolism in young humans are relatively unexplored.

objectivesTo investigate possible associations between magnetic resonance imaging (MRI) estimates of BAT and glucose metabolism, whilst considering sex, age, and adiposity, in adolescents with normal and overweight/obese phenotypes.

methodsIn 143 subjects (10-20 years), MRI estimates of BAT were assessed as cervical-supraclavicular adipose tissue (sBAT) fat fraction (FF) and

resultssBAT FF and

conclusionsThe association between sBAT FF and 2h glucose, observed independently of sex, age, adiposity, and SAT FF, indicates a role for BAT in glucose metabolism, which potentially could influence the risk of developing diabetes. The lacking association with sBAT

Indexed as

Adipose Tissue, BrownAdolescentAdultAustriaChildFemaleGlucoseHumansMagnetic Resonance ImagingMaleOverweightSwedenYoung AdultGlucoseadolescentbrown adipose tissueglucose metabolismmagnetic resonance imaging

Identifiers

PMID31290284
PMCPMC6771901

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.