Evidence map›Paper›PMID 31290107›Full record

ArticleObesity surgery2019

Differential Effects of Roux-en-Y Gastric Bypass Surgery and Laparoscopic Sleeve Gastrectomy on Fatty Acid Levels.

Sudipa Sarkar, Frederick Anokye-Danso, Jena Shaw Tronieri, John S Millar, Naji Alamuddin, Thomas A Wadden, Rexford S Ahima

Registry-linked trialOpen access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Obesity surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01228097 (Changes in Neural Response to Eating After Bariatric Surgery), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01228097 completednot on this map

Changes in Neural Response to Eating After Bariatric Surgery: MRI Results

TypeobservationalSponsorUniversity of PennsylvaniaRan2010 to 2015Enrolled75ConditionsObesity
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sudipa SarkarDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD, USA. ssarka19@jhmi.edu.ORCID http://orcid.org/0000-0002-1838-2401
Frederick Anokye-DansoDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Jena Shaw TronieriDepartment of Psychiatry, Center for Weight and Eating Disorders, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
John S MillarMetabolic Tracer Resource, Institute for Diabetes, Obesity and Metabolism, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Naji AlamuddinDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Thomas A WaddenDepartment of Psychiatry, Center for Weight and Eating Disorders, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Rexford S AhimaDepartment of Medicine, Division of Endocrinology, Diabetes and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD, USA.
University of Pennsylvania · USJohns Hopkins University · US

Funding

Changes in neural response to eating after bariatric surgery: MRI resultsR01DK085615 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI GUR, RUBEN C., WADDEN, THOMAS A. · 2010 to 2014
$2.8M
Improving Weight Loss in Early Non-responders to Behavioral TreatmentK23DK116935 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI TRONIERI, JENNIFER SHAW · 2019 to 2023
$938k
NIDDK NIH HHS K23 DK116935NIDDK NIH HHS R01 DK085615
6 · The paper itself

Abstract

backgroundBariatric surgery is associated with improved cardiovascular outcomes and also affects lipid levels, but few studies have compared the effects of Roux-en-Y gastric bypass (RYGB) surgery with those of laparoscopic sleeve gastrectomy (LSG) on serum fatty acid levels. The present study compares the effects of RYGB and LSG surgeries on serum fatty acid levels.

methodsThe study participants were women who were undergoing either RYGB or LSG and body mass index (BMI)-matched controls. Fasting blood samples to measure glucose, insulin, and fatty acids were drawn at baseline and at 6 and 18 months from baseline.

resultsSerum fatty acid data were available for 57 participants at baseline, of whom 56 had data at 6 months and 41 had data at 18 months from baseline. Compared with baseline, serum non-esterified fatty acids (NEFAs) levels were significantly higher at 6 and 18 months in the LSG group compared with the RYGB group. In the RYGB group, 2 saturated fatty acids (SFAs), 2 monounsaturated fatty acids (MUFAs), and 1 polyunsaturated fatty acid (PUFA) were significantly decreased after surgery, compared with those of the LSG group.

conclusionsA significant increase in NEFAs was seen after LSG, compared with RYGB. Compared with the LSG group, several serum fatty acids were significantly reduced after RYGB.

trial registrationNCT01228097.

Indexed as

GastrectomyGastric BypassAdultBiomarkersCase-Control StudiesFatty AcidsFemaleFollow-Up StudiesHumansMiddle AgedObesity, MorbidPostoperative PeriodTreatment OutcomeBiomarkersFatty AcidsFatty acidsGastric bypass surgeryLipidsObesitySleeve gastrectomy

Identifiers

PMID31290107
PMCPMC6920534
OpenAlexW2956340745

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.