Evidence map›Paper›PMID 31290106›Full record

ArticleObesity surgery2019

Roux Limb Motility in Gastric Bypass Patients with Chronic Abdominal Pain-Is There an Association to Prescribed Opioids?

Per Björklund, Almantas Maleckas, Hans Lönroth, Niclas Björnfot, Sven Egron Thörn, Lars Fändriks

Open access · hybridAbstract read
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In one paragraph

Article in Obesity surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Per BjörklundDepartment of Gastrosurgical Research and Education, Institute of Clinical Sciences, The Sahlgrenska Academy, Sahlgrenska University Hospital, University of Gothenburg, SE41345, Gothenburg, Sweden.
Almantas MaleckasDepartment of Gastrosurgical Research and Education, Institute of Clinical Sciences, The Sahlgrenska Academy, Sahlgrenska University Hospital, University of Gothenburg, SE41345, Gothenburg, Sweden.
Hans LönrothDepartment of Gastrosurgical Research and Education, Institute of Clinical Sciences, The Sahlgrenska Academy, Sahlgrenska University Hospital, University of Gothenburg, SE41345, Gothenburg, Sweden.
Niclas BjörnfotDepartment of Gastrosurgical Research and Education, Institute of Clinical Sciences, The Sahlgrenska Academy, Sahlgrenska University Hospital, University of Gothenburg, SE41345, Gothenburg, Sweden.
Sven Egron ThörnDepartment of Anesthesiology and Intensive Care, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Lars FändriksDepartment of Gastrosurgical Research and Education, Institute of Clinical Sciences, The Sahlgrenska Academy, Sahlgrenska University Hospital, University of Gothenburg, SE41345, Gothenburg, Sweden. lars.fandriks@gastro.gu.se.ORCID http://orcid.org/0000-0003-0736-3034
Sahlgrenska University Hospital · SELithuanian University of Health Sciences · LTUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimA number of patients continue to suffer from chronic abdominal pain of unknown origin, which may also lead to a prolonged use of opioid analgesics. Symptoms of abdominal pain, nausea and vomiting in this patient group resemble the characteristics of the Roux stasis Syndrome. The aim was to elucidate relationships between chronic abdominal pain, Roux limb motor activity and opioid analgesics.

methodsRoux limb high-resolution manometry and ratings of abdominal pain and quality of life were analysed in 15 gastric bypass patients reporting abdominal pain of unknown origin. Effect of acute opiate administration (morphine i.v.) on fasting Roux limb motor activity was assessed in asymptomatic and morphine-naïve gastric bypass patients (n = 9) and compared with an untreated control group (n = 11).

resultsIn the symptomatic patient group, we found disturbed Roux limb motor patterns in 10 out of 15 examinations, but no signs of Roux stasis syndrome. A high prevalence of prescribed opioid analgesics as well as a high number of reoperations in this group. The worst quality of life and the highest number of pain-killing medications were observed among the patients with distal pacemaker activity in Roux limb. In the morphine-naïve and asymptomatic patients, morphine increased the muscular tone in the Roux limb during phase III-like motor activity. A majority of the RYGBP patients with chronic abdominal pain had a disturbed Roux limb fasting motility, and there was a high prevalence of prescribed opioid analgesics. In opiate-naïve RYGBP patients, acute morphine intravenously increased the muscular tone of the Roux limb.

Indexed as

Gastric BypassAbdominal PainAdultAnalgesics, OpioidCase-Control StudiesChronic PainFemaleGastrointestinal MotilityHumansMaleMiddle AgedObesity, MorbidPain MeasurementPostoperative ComplicationsPostoperative PainQuality of LifeAnalgesics, OpioidBariatricIntestinal motilityManometryOpiates

Identifiers

PMID31290106
OpenAlexW2960326418

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.