Evidence map›Paper›PMID 31289970›Full record

ReviewJournal of muscle research and cell motility2020

Calcium-dependent titin-thin filament interactions in muscle: observations and theory.

Kiisa Nishikawa, Samrat Dutta, Michael DuVall, Brent Nelson, Matthew J Gage, Jenna A Monroy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of muscle research and cell motility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  9. The distinctive mechanical and structural signatures of residual force enhancement in myofibers.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kiisa NishikawaDepartment of Biological Sciences, Northern Arizona University, Flagstaff, AZ, 86011-4185, USA. Kiisa.Nishikawa@nau.edu.ORCID 0000-0001-8252-0285
Samrat DuttaDepartment of Biological Sciences, Northern Arizona University, Flagstaff, AZ, 86011-4185, USA.
Michael DuVallDepartment of Biological Sciences, Northern Arizona University, Flagstaff, AZ, 86011-4185, USA.
Brent NelsonDepartment of Mechanical Engineering, Northern Arizona University, Flagstaff, AZ, 86011-15600, USA.
Matthew J GageChemistry Department, University of Massachusetts at Lowell, Lowell, MA, 01854, USA.ORCID 0000-0003-2304-6960
Jenna A MonroyW. M. Keck Science Center, Claremont Colleges, Claremont, CA, 91711-5916, USA.ORCID 0000-0001-7635-8613
Northern Arizona University · USUniversity of Massachusetts Lowell · USW.M. Keck Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gaps in our understanding of muscle mechanics demonstrate that the current model is incomplete. Increasingly, it appears that a role for titin in active muscle contraction might help to fill these gaps. While such a role for titin is increasingly accepted, the underlying molecular mechanisms remain unclear. The goals of this paper are to review recent studies demonstrating Ca

Indexed as

CalciumConnectinHumansMuscle ProteinsCalciumConnectinMuscle ProteinsTTN protein, humanForce transmissionMuscle activationMuscle mechanicsSarcomere integrityTitin passive stiffness

Identifiers

PMID31289970
OpenAlexW2961802821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.