Evidence map›Paper›PMID 31289922›Full record

ReviewCurrent gastroenterology reports2019

The Utility of Esophageal Motility Testing in Gastroesophageal Reflux Disease (GERD).

Stephanie Garbarino, Anthony Horton, Amit Patel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. ACG Clinical Guidelines: Clinical Use of Esophageal Physiologic Testing.The American journal of gastroenterology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Stephanie GarbarinoDivision of Gastroenterology, Duke University School of Medicine and the Durham Veterans Affairs Medical Center, 10207 Cerny St, Suite 210, Raleigh, NC, 27617, USA.
Anthony HortonDivision of Gastroenterology, Duke University School of Medicine and the Durham Veterans Affairs Medical Center, 10207 Cerny St, Suite 210, Raleigh, NC, 27617, USA.
Amit PatelDivision of Gastroenterology, Duke University School of Medicine and the Durham Veterans Affairs Medical Center, 10207 Cerny St, Suite 210, Raleigh, NC, 27617, USA. amit.patel@duke.edu.
Duke University · USDurham VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewHere, we discuss how esophageal motor testing plays important roles in patients with suspected gastroesophageal reflux disease (GERD). In addition to guiding appropriate placement of catheters for ambulatory reflux monitoring, esophageal high-resolution manometry (HRM) rules out confounding diagnoses, such as achalasia spectrum disorders, that can present with symptoms similar to that of GERD, but are managed very differently. RECENT

findingsHRM performed with impedance in the post-prandial setting (PP-HRIM) can assess for rumination syndrome or supragastric belching, which should be directed towards behavioral interventions. The recent GERD Classification of Motor Function recommends a hierarchical approach, focusing on (1) the esophagogastric junction (EGJ), (2) the esophageal body, and (3) esophageal contraction reserve, which can be assessed with provocative maneuvers at HRM, such as multiple rapid swallows (MRS). This approach can inform the appropriate tailoring of antireflux surgery. Novel esophageal motility metrics, such as the EGJ-contractile integral from HRM, or post-reflux swallow-induced peristaltic wave indices from 24-h pH-impedance monitoring, may also assist with GERD diagnosis. Assessment of esophageal motor function can contribute in a significant manner to the care of patients with suspected GERD, particularly when esophageal symptoms do not improve with antisecretory therapy, and/or when surgical or endoscopic antireflux therapies are under consideration.

Indexed as

Diagnosis, DifferentialEsophageal AchalasiaEsophagogastric JunctionEsophagusGastroesophageal RefluxHumansManometryMonitoring, AmbulatoryPeristalsisRumination SyndromeAchalasiaAntireflux surgery (ARS)Esophageal function testingEsophageal high-resolution manometry (HRM)Esophageal motor testingGastroesophageal reflux disease (GERD)High-resolution impedance manometry (HRIM)Multiple rapid swallows (MRS)

Identifiers

PMID31289922
OpenAlexW2956461959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.