Evidence map›Paper›PMID 31289847›Full record

ArticleCurrent microbiology2019

The Xanthomonas citri pv. citri Type VI Secretion System is Induced During Epiphytic Colonization of Citrus.

Lucas M Ceseti, Eliane S de Santana, Camila Y Ratagami, Yasmin Barreiros, Lídia Dos Passos Lima, German Dunger, Chuck S Farah, Cristina E Alvarez-Martinez

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Biology · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Secrete or perish: The role of secretion systems inComputational and structural biotechnology journal · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lucas M CesetiDepartamento de Genética, Evolução, Microbiologia e Imunologia, Instituto de Biologia, Universidade Estadual de Campinas (Unicamp), Rua Monteiro Lobato, 255, Campinas, SP, 13083-862, Brazil.
Eliane S de SantanaDepartamento de Genética, Evolução, Microbiologia e Imunologia, Instituto de Biologia, Universidade Estadual de Campinas (Unicamp), Rua Monteiro Lobato, 255, Campinas, SP, 13083-862, Brazil.
Camila Y RatagamiDepartamento de Genética, Evolução, Microbiologia e Imunologia, Instituto de Biologia, Universidade Estadual de Campinas (Unicamp), Rua Monteiro Lobato, 255, Campinas, SP, 13083-862, Brazil.
Yasmin BarreirosDepartamento de Genética, Evolução, Microbiologia e Imunologia, Instituto de Biologia, Universidade Estadual de Campinas (Unicamp), Rua Monteiro Lobato, 255, Campinas, SP, 13083-862, Brazil.
Lídia Dos Passos LimaDepartamento de Genética, Evolução, Microbiologia e Imunologia, Instituto de Biologia, Universidade Estadual de Campinas (Unicamp), Rua Monteiro Lobato, 255, Campinas, SP, 13083-862, Brazil.
German DungerDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo (USP), Av. Prof. Lineu Prestes 748 Bloco 0, sala 10, São Paulo, SP, 05508-900, Brazil.
Chuck S FarahDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo (USP), Av. Prof. Lineu Prestes 748 Bloco 0, sala 10, São Paulo, SP, 05508-900, Brazil.
Cristina E Alvarez-MartinezDepartamento de Genética, Evolução, Microbiologia e Imunologia, Instituto de Biologia, Universidade Estadual de Campinas (Unicamp), Rua Monteiro Lobato, 255, Campinas, SP, 13083-862, Brazil. ceamarti@unicamp.br.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (BR) 001Fundação de Amparo à Pesquisa do Estado de São Paulo 18/01852-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2011/07777-5Fundação de Amparo à Pesquisa do Estado de São Paulo 2014/19720-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2014/25261-4Fundação de Amparo à Pesquisa do Estado de São Paulo 2016/08400-6Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/02318-9
6 · The paper itself

Abstract

Xanthomonas citri pv. citri (X. citri pv. citri) is the causal agent of Asiatic citrus canker and infects economically important citrus crops. X. citri pv. citri contains one type VI secretion system (T6SS) required for resistance to predation by the soil amoeba Dictyostelium discoideum and induced by the ECF sigma factor EcfK in the presence of amoeba. In this work, we describe the analysis of T6SS gene expression during interaction with host plants. We show that T6SS genes and the cognate positive regulator ecfK are upregulated during growth in the plant surface (epiphytic) and maintain low expression levels during growth inside plant mesophyll. In addition, expression of the virulence-associated T3SS is also induced during epiphytic growth and shows a temporal induction pattern during growth inside plant leaves. The T6SS is not required for adhesion to leaf surface and biofilm formation during the first stages of plant colonization nor for killing of yeasts cells. Since the phyllosphere is colonized by eukaryotic predators of bacteria, induction of the X. citri pv. citri anti-amoeba T6SS during epiphytic growth suggests the presence of an environmental signal that triggers the resistance phenotype.

Indexed as

Gene Expression Regulation, BacterialBacterial ProteinsCitrusMutationPlant DiseasesPlant LeavesSigma FactorType VI Secretion SystemsVirulenceXanthomonasBacterial ProteinsSigma FactorType VI Secretion Systems

Identifiers

PMID31289847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.