Evidence map›Paper›PMID 31289745›Full record

ArticleInternational journal of cardiology. Heart & vasculature2019

Association between reactive hyperemia peripheral arterial tonometry index and atrial fibrillation recurrence after catheter ablation.

Hideki Kobayashi, Ayako Okada, Hiroaki Tabata, Wataru Shoin, Takahiro Okano, Koji Yoshie, Yasutaka Oguchi, Ken Kato, Morio Shoda, Koichiro Kuwahara

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Impact of pulse duration on cardiac electroporation: nanosecond pulses enhance cardiomyocyte selectivity and promote a Raman-detected shift towards apoptotic cell death.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  2. Article
  3. Article
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  6. Risk profiling in atrial fibrillation: Value of assessment of vascular blush.International journal of cardiology. Heart & vasculature · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hideki KobayashiDepartment of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, Japan.
Ayako OkadaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, Japan.
Hiroaki TabataDepartment of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, Japan.
Wataru ShoinDepartment of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, Japan.
Takahiro OkanoDepartment of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, Japan.
Koji YoshieDepartment of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, Japan.
Yasutaka OguchiDepartment of Cardiovascular Medicine, Aizawa Hospital, Nagano, Japan.
Ken KatoDepartment of Cardiology, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan.
Morio ShodaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, Japan.
Koichiro KuwaharaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine, Nagano, Japan.
Shinshu University · JPAizawa Hospital · JPTokyo Metropolitan Tama Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVascular endothelial function has recently been recognized as an independent predictor of cardiovascular events. However, studies investigating its association with atrial fibrillation (AF) are lacking. This study aimed to examine association with AF recurrence and vascular endothelial function as assessed using natural logarithmic transformation of reactive hyperemia peripheral arterial tonometry index (LnRHI).

methodsNinety-nine consecutive AF patients who underwent catheter ablation (CA) at Shinshu University Hospital between September 2015 and April 2017 were enrolled. LnRHI was measured 48 to 72 h before CA using the EndoPAT system. The primary outcome was AF recurrence beyond 3 months post-ablation.

resultsA total of 30 (30.3%) patients experienced AF recurrence after CA over a median follow-up period of 210 days (range: 93-764 days). Female sex and low LnRHI were significantly associated with AF recurrence. In multivariate analysis, LnRHI was an independent predictor of AF recurrence (hazard ratio: 0.087, 95% confidence interval 0.015-0.51, p = 0.007). In comparison in Kaplan-Meier analysis of high LnRHI (LnRHI ≥0.52, n = 52) and low LnRHI (LnRHI ≪0.52, n = 47) groups, AF recurrence rate was significantly higher in the low LnRHI group (log-rank test, p = 0.043). A negative correlation was observed between LnRHI and AF duration, whereby LnRHI was significantly decreased when the duration of AF events exceeded 1 year.

conclusionDecreased LnRHI was associated with AF recurrence after CA and prolonged AF duration.

Indexed as

Atrial fibrillationCatheter ablationNatural logarithmic transformation of reactive hyperemia peripheral arterial tonometry index (LnRHI)Vascular endothelial function

Identifiers

PMID31289745
PMCPMC6593202
OpenAlexW2949335825

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.