Evidence map›Paper›PMID 31289507›Full record

ArticleOncology letters2019

Survivin is a prognostic indicator in glioblastoma and may be a target of microRNA-218.

Xuezhi Tong, Pei Yang, Kuanyu Wang, Yanwei Liu, Xiu Liu, Xia Shan, Ruoyu Huang, Ke'Nan Zhang, Jiangfei Wang

Abstract read
In one paragraph

Article in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Immunotherapy for Glioma: A compartmental framework for resistance and rational combination design.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
  3. Mechanotherapeutic Potential of Survivin in Glioblastoma.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
  6. Targeting Survivin: Now I Become Death, the Destroyer of Cells.International journal of molecular sciences · 2025
    Review
  7. Review
  8. Cell death in glioblastoma and the central nervous system.Cellular oncology (Dordrecht, Netherlands) · 2025
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Normofractionated irradiation and not temozolomide modulates the immunogenic and oncogenic phenotype of human glioblastoma cell lines.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Article
  15. Article
  16. Cellular senescence in glioma.Journal of neuro-oncology · 2023
    Review
  17. Article
  18. Review
  19. The Chromatin-Oxygen Sensor GeneInternational journal of molecular sciences · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xuezhi TongDepartment of Neurosurgery, Beijing Tiantan Hospital, Beijing 100050, P.R. China.
Pei YangDepartment of Neurosurgery, Beijing Tiantan Hospital, Beijing 100050, P.R. China.
Kuanyu WangDepartment of Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, P.R. China.
Yanwei LiuDepartment of Neurosurgery, Beijing Tiantan Hospital, Beijing 100050, P.R. China.
Xiu LiuDepartment of Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, P.R. China.
Xia ShanDepartment of Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, P.R. China.
Ruoyu HuangDepartment of Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, P.R. China.
Ke'Nan ZhangDepartment of Neurosurgery, Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, P.R. China.
Jiangfei WangDepartment of Neurosurgery, Beijing Tiantan Hospital, Beijing 100050, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence has revealed that survivin expression is associated with a malignant phenotype and poor prognosis in glioma. Survivin is also a potential target of microRNA (miRNA/miR)-218. The aim of the present study was to investigate the expression and function of survivin in glioblastoma, and to examine the association between survivin and miR-218. For that purpose, survivin mRNA levels were analyzed in 144 frozen samples of glioblastoma using whole-genome RNA sequencing.

Indexed as

glioblastomamiRNA-218prognosisproliferationsurvivin

Identifiers

PMID31289507
PMCPMC6539917

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.