Evidence map›Paper›PMID 31289334›Full record

ArticleInternational journal of obesity (2005)2020

The effects of exercise session timing on weight loss and components of energy balance: midwest exercise trial 2.

Erik A Willis, Seth A Creasy, Jeffery J Honas, Edward L Melanson, Joseph E Donnelly

Open access · hybridAbstract read
In one paragraph

Article in International journal of obesity (2005), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 3 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 3 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Timing of physical activity within the 24-hour day and its influence on health: a systematic review.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2022
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4 · The record

Corrections and comments

  • Commented on by
    2020
5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Erik A WillisCenter for Health Promotion and Disease Prevention, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA. erik.willis@unc.edu.
Seth A CreasyDivision of Endocrinology, Metabolism, and Diabetes, Anschutz Medical Campus, University of Colorado Aurora, Aurora, CO, USA.ORCID http://orcid.org/0000-0002-4176-0917
Jeffery J HonasDepartment of Internal Medicine, The University of Kansas Medical Center, Kansas City, KS, USA.
Edward L MelansonDivision of Endocrinology, Metabolism, and Diabetes, Anschutz Medical Campus, University of Colorado Aurora, Aurora, CO, USA.
Joseph E DonnellyDepartment of Internal Medicine, The University of Kansas Medical Center, Kansas City, KS, USA.
University of Kansas Medical Center · USGeriatric Research Education and Clinical Center · USUniversity of Colorado Anschutz Medical Campus · USUniversity of North Carolina at Chapel Hill · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
LONG-TERM EXERCISE WEIGHT LOSS AND ENERGY BALANCER01DK049181 · NIDDK · UNIVERSITY OF NEBRASKA KEARNEY · PI DONNELLY, JOSEPH E. · 1996 to 2009
$3.1M
Linking temporal patterns of modifiable behaviors to weight loss outcomesK01HL145023 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI CREASY, SETH A · 2019 to 2023
$820k
NHLBI NIH HHS K01 HL145023NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK049181
6 · The paper itself

Abstract

BACKGROUND/

objectivesCircadian physiology has been linked to body weight regulation and obesity. To date, few studies have assessed the association between exercise timing and weight related outcomes. The aim of this secondary analysis was to explore the impact of exercise timing (i.e., 24 h clock time of exercise session) on weight loss and components of energy balance. SUBJECTS/

methodsOverweight/obese (BMI 25.0-39.9 kg/m

resultsAt month 10, weight loss was significantly greater in both Early-EX (-7.2 ± 1.2%; p < 0.001) and Sporadic-EX (- 5.5 ± 1.2%; p = 0.01) vs CON (+0.5 ± 1.0%), and Early-EX vs Late-EX (-2.1 ± 1.0%; p < 0.001). There were no between group differences for change in TDEE, EI, and non-exercise energy expenditure (P > 0.05). A significant group × time interaction (p = 0.02) was observed for NEPA (counts/min), however, after adjusting for multiple comparisons, group effects were no longer significant.

conclusionsDespite minimal differences in components of energy balance, Early-EX lost significantly more weight compared with Late-Ex. Although the mechanisms are unclear, the timing of exercise may be important for body weight regulation.

Indexed as

AdultCircadian ClocksEnergy IntakeEnergy MetabolismExerciseFemaleHumansMaleObesityRandomized Controlled Trials as TopicSedentary BehaviorTime FactorsWeight LossYoung Adult

Identifiers

PMID31289334
PMCPMC6925313
OpenAlexW2957644725

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.